Evidence map›Paper›PMID 32230810›Full record

ArticleInternational journal of molecular sciences2020

Enhancement of Biomimetic Enzymatic Mineralization of Gellan Gum Polysaccharide Hydrogels by Plant-Derived Gallotannins.

Timothy E L Douglas, Julia K Keppler, Marta Vandrovcová, Martin Plencner, Jana Beranová, Michelle Feuereisen, Bogdan V Parakhonskiy, Yulia Svenskaya, Vsevolod Atkin, Anna Ivanova and 6 more

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In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 6 countries.

Timothy E L DouglasNano-Biotechnology Group, Department of Biotechology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.
Julia K KepplerDivision of Food Technology, Kiel University, 24118 Kiel, Germany.ORCID 0000-0003-4183-1794
Marta VandrovcováDepartment of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, 142 00 Prague, Czech Republic.ORCID 0000-0001-8632-5321
Martin PlencnerDepartment of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, 142 00 Prague, Czech Republic.
Jana BeranováDepartment of Genetics and Microbiology, Charles University in Prague, 116 36 Prague, Czech Republic.
Michelle FeuereisenDepartment of Nutritional and Food Sciences, University of Bonn, D-53012 Bonn, Germany.
Bogdan V ParakhonskiyNano-Biotechnology Group, Department of Biotechology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-6481-3700
Yulia SvenskayaInstitute of Nanostructures and Biosystems, Saratov NG Chernyshevskii State Univ, 83 Astrakhanskaya St, 410012 Saratov, Russia.ORCID 0000-0002-6359-2969
Vsevolod AtkinInstitute of Nanostructures and Biosystems, Saratov NG Chernyshevskii State Univ, 83 Astrakhanskaya St, 410012 Saratov, Russia.
Anna IvanovaFSRC "Crystallography and photonics" RAS, 119333 Moscow, Russia.ORCID 0000-0003-4497-8863
Patrick RicquierOmnichem NV, 9230 Wetterem, Belgium.
Lieve BalcaenDepartment of Chemistry, Ghent University, Krijgslaan 281, 9000 Ghent, Belgium.
Frank VanhaeckeDepartment of Chemistry, Ghent University, Krijgslaan 281, 9000 Ghent, Belgium.
Andreas SchieberDepartment of Nutritional and Food Sciences, University of Bonn, D-53012 Bonn, Germany.
Lucie BačákováDepartment of Biomaterials and Tissue Engineering, Institute of Physiology of the Czech Academy of Sciences, 142 00 Prague, Czech Republic.ORCID 0000-0002-1818-9484
Andre G SkirtachNano-Biotechnology Group, Department of Biotechology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium.
Ghent University · BECzech Academy of Sciences · CZSaratov State University · RUUniversity of Bonn · DECharles University · CZChristian-Albrechts-Universität zu Kiel · DEFederal Scientific Research Centre Crystallography and Photonics · RU

Funding

BOF (Bijzonder Onzderzoeksfonds) of Ghent University, Belgium A.G.S.Czech science foundation 17-00885SDeutsche Forschungsgemeinschaft J.K.K.Fonds Wetenschappelijk Onderzoek Postdoctoral Fellowships, travel grant
6 · The paper itself

Abstract

Mineralization of hydrogel biomaterials with calcium phosphate (CaP) is considered advantageous for bone regeneration. Mineralization can be both induced by the enzyme alkaline phosphatase (ALP) and promoted by calcium-binding biomolecules, such as plant-derived polyphenols. In this study, ALP-loaded gellan gum (GG) hydrogels were enriched with gallotannins, a subclass of polyphenols. Five preparations were compared, namely three tannic acids of differing molecular weight (MW), pentagalloyl glucose (PGG), and a gallotannin-rich extract from mango kernel (

Indexed as

Alkaline PhosphataseAnti-Bacterial AgentsBiocompatible MaterialsBiomimeticsBone RegenerationCalcification, PhysiologicCalcium PhosphatesHumansHydrogelsHydrolyzable TanninsMangiferaMineralsOsteoblastsPlant ExtractsPlantsPolyphenolsAlkaline PhosphataseAnti-Bacterial AgentsBiocompatible Materialscalcium phosphateCalcium Phosphatesgellan gumHydrogelsHydrolyzable TanninsMangifera indica extractMineralspentagalloylglucosePlant ExtractsPolyphenolsPolysaccharidesPolysaccharides, Bacterialcompositeenzymegellan gummineralizationpolyphenolprotein-polyphenol interaction

Identifiers

PMID32230810
PMCPMC7177887
OpenAlexW3013732644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.