Evidence map›Paper›PMID 32230809›Full record

ReviewCancers2020

The Role of Positron Emission Tomography in Clinical Management of Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Simone Serafini, Cosimo Sperti, Alessandra Rosalba Brazzale, Diego Cecchin, Pietro Zucchetta, Elisa Sefora Pierobon, Alberto Ponzoni, Michele Valmasoni, Lucia Moletta

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm.Biochimica et biophysica acta. Reviews on cancer · 2023
    Review
  4. Article
  5. State-of-the-Art Update of Pancreatic Cysts.Digestive diseases and sciences · 2022
    Review
  6. Article
  7. Review
  8. SupplementalCancers · 2021
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Simone SerafiniDepartment of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.
Cosimo SpertiDepartment of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.
Alessandra Rosalba BrazzaleDepartment of Statistical Sciences, University of Padua, 35122 Padua, Italy.ORCID 0000-0003-1989-2697
Diego CecchinDepartment of Medicine, Nuclear Medicine Unit, University of Padua, 35122 Padua, Italy.
Pietro ZucchettaDepartment of Medicine, Nuclear Medicine Unit, University of Padua, 35122 Padua, Italy.
Elisa Sefora PierobonDepartment of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.ORCID 0000-0002-5836-1197
Alberto PonzoniDepartment of Radiology, Padua General Hospital, 35121 Padua, Italy.
Michele ValmasoniDepartment of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.ORCID 0000-0002-1462-8275
Lucia MolettaDepartment of Surgery, Oncology and Gastroenterology, 3rd Surgical Clinic, University of Padua, 35122 Padua, Italy.ORCID 0000-0003-4041-5721
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas represent a heterogeneous group of tumors, increasingly diagnosed in clinical practice. An early differential diagnosis between malignant and benign lesions is crucial to patient management and the choice of surgery or observation. The therapeutic approach is currently based on a patient's clinical, biochemical, and morphological characteristics. The latest published International Consensus Guidelines (ICG) make no mention of the role of metabolic assessments of IPMNs. The aim of this study was to review the current literature, examining the role of 18-fluorodeoxyglucose (FDG) positron emission tomography (PET) in IPMN management. An extensive literature review was conducted according to the 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and 10 articles were analyzed in detail, focusing on the value of PET as opposed to other standard imaging criteria. Data were retrieved on 419 patients. The 18-FDG-PET proved more sensitive, specific, and accurate than the ICG criteria in detecting malignant IPMNs (reaching 80%, 95%, and 87% vs. 67%, 58%, and 63%, respectively). Metabolic assessments may be used as an additional tool for the appropriate management of patients with doubtful imaging findings.

Indexed as

cystic tumorInternational Consensus Guidelinesintraductal papillary mucinous neoplasmspancreatic neoplasmspositron emission tomography

Identifiers

PMID32230809
PMCPMC7226258
OpenAlexW3013147659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.