Evidence map›Paper›PMID 32230800›Full record

ArticleGenes2020

Influence of Genetic Variation in

Bram C Agema, Stijn L W Koolen, Mirjam de With, Nadia van Doorn, Niels Heersche, Esther Oomen-de Hoop, Sabine Visser, Joachim G J V Aerts, Sander Bins, Ron H N van Schaik and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bram C AgemaDepartment of Clinical Chemistry, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Stijn L W KoolenDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Mirjam de WithDepartment of Clinical Chemistry, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Nadia van DoornDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Niels HeerscheDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Esther Oomen-de HoopDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Sabine VisserDepartment of Pulmonology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Joachim G J V AertsDepartment of Pulmonology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Sander BinsDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Ron H N van SchaikDepartment of Clinical Chemistry, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Ron H J MathijssenDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cisplatin is a chemotherapeutic agent widely used for multiple indications. Unfortunately, in a substantial set of patients treated with cisplatin, dose-limiting acute kidney injury (AKI) occurs. Here, we assessed the association of 3 catechol-O-methyltransferase (

Indexed as

Polymorphism, Single NucleotideAcute Kidney InjuryAgedAntineoplastic Combined Chemotherapy ProtocolsCatechol O-MethyltransferaseCisplatinFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasmsPemetrexedPrognosisProspective StudiesCatechol O-MethyltransferaseCisplatinCOMT protein, humanPemetrexedacute kidney injurycisplatinCOMTnephrotoxicitySNP

Identifiers

PMID32230800
PMCPMC7230333
OpenAlexW3013593553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.