Evidence map›Paper›PMID 32230722›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Internalized FGF-2-Loaded Nanoparticles Increase Nuclear ERK1/2 Content and Result in Lung Cancer Cell Death.

Tianxin Miao, Andrew C Little, Alexander Aronshtam, Taylor Marquis, Spencer L Fenn, Milena Hristova, Dimitry N Krementsov, Albert van der Vliet, Jeffrey L Spees, Rachael A Oldinski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tianxin MiaoBioengineering Program, College of Engineering and Mathematical Sciences, Larner College of Medicine, College of Engineering and Mathematical Sciences, University of Vermont, Burlington VT 05405, USA.
Andrew C LittleCellular, Molecular and Biomedical Sciences Graduate Program, University of Vermont, Burlington, Vermont 05405, USA.
Alexander AronshtamDepartment of Medicine, Stem Cell Core, Larner College of Medicine, University of Vermont, Colchester, VT 05446, USA.
Taylor MarquisDepartment of Medicine, Stem Cell Core, Larner College of Medicine, University of Vermont, Colchester, VT 05446, USA.
Spencer L FennBioengineering Program, College of Engineering and Mathematical Sciences, Larner College of Medicine, College of Engineering and Mathematical Sciences, University of Vermont, Burlington VT 05405, USA.
Milena HristovaDepartment of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, VT 05405, USA.
Dimitry N KrementsovDepartment of Biomedical and Health Sciences, College of Nursing and Health Sciences, University of Vermont, Burlington, Vermont 05405, USA.
Albert van der VlietCellular, Molecular and Biomedical Sciences Graduate Program, University of Vermont, Burlington, Vermont 05405, USA.
Jeffrey L SpeesCellular, Molecular and Biomedical Sciences Graduate Program, University of Vermont, Burlington, Vermont 05405, USA.
Rachael A OldinskiBioengineering Program, College of Engineering and Mathematical Sciences, Larner College of Medicine, College of Engineering and Mathematical Sciences, University of Vermont, Burlington VT 05405, USA.
University of Vermont · US

Funding

Dual Oxidase in Airway Epithelial Repair and RemodelingR01HL085646 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI VAN DER VLIET, ALBERT · 2008 to 2020
$4.7M
Factors Responsible for Cardiac Preservation Conferred by Adult Marrow Stem CellsR01HL085210 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPEES, JEFFREY L · 2008 to 2012
$1.7M
Vascular protection by HGF/IgG protein complexes that activate RYKR01HL132264 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPEES, JEFFREY L · 2016 to 2019
$1.5M
Control of reactive astrocytes by Notch1 and Amyloid Precursor ProteinR01NS073815 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPEES, JEFFREY L · 2012 to 2015
$1.3M
NHLBI NIH HHS R01 HL132264NIH HHS R01HL085210NIH HHS R01HL085646NIH HHS R01HL132264NIH HHS R01NS073815
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer cell deathERK1/2intracellular FGF-2lung cancernanoparticles

Identifiers

PMID32230722
PMCPMC7221911
OpenAlexW3014071022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.