Evidence map›Paper›PMID 32230714›Full record

ArticleCancers2020

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen.

Anieta M Sieuwerts, Márcia A Inda, Marcel Smid, Henk van Ooijen, Anja van de Stolpe, John W M Martens, Wim F J Verhaegh

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
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  3. Real-world application ofEuropean journal of nuclear medicine and molecular imaging · 2026
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  8. Evaluation of tumour heterogeneity byBreast cancer research : BCR · 2022
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anieta M SieuwertsDepartment of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus MC, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Márcia A IndaPhilips Research, Precision Diagnostics Department, High Tech Campus 11, 5656 AE Eindhoven, The Netherlands.
Marcel SmidDepartment of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus MC, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Henk van OoijenPhilips Research, Precision Diagnostics Department, High Tech Campus 11, 5656 AE Eindhoven, The Netherlands.
Anja van de StolpePhilips Research, Precision Diagnostics Department, High Tech Campus 11, 5656 AE Eindhoven, The Netherlands.
John W M MartensDepartment of Medical Oncology and Cancer Genomics Netherlands, Erasmus MC Cancer Institute, Erasmus MC, Doctor Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Wim F J VerhaeghPhilips Research, Precision Diagnostics Department, High Tech Campus 11, 5656 AE Eindhoven, The Netherlands.
Philips (Netherlands) · NLErasmus MC Cancer Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bayesian networkfunctional activitymetastasismRNA expressionprogression-free survivalsignaling pathwaytamoxifentreatment response

Identifiers

PMID32230714
PMCPMC7226576
OpenAlexW3013664357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.