Evidence map›Paper›PMID 32230711›Full record

SynthesisInternational journal of environmental research and public health2020

A Systematic Literature Review of E-Cigarette-Related Illness and Injury: Not Just for the Respirologist.

Anna Tzortzi, Melpo Kapetanstrataki, Vaso Evangelopoulou, Panagiotis Beghrakis

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Vaping-related lung disease: a narrative review.Journal of thoracic disease · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Development of Chatbot-Assisted Smoking Cessation Telehealth Intervention: A Case Report.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  14. E-cigarette use-associated lung injury (EVALI).Pneumologie (Stuttgart, Germany) · 2024
    Article
  15. Heated tobacco product (IQOS) induced pulmonary infiltrates.Respiratory medicine case reports · 2024
    Article
  16. Article
  17. Review
  18. A Survey of Vaping Use, Perceptions, and Access in Adolescents from South-Central Texas Schools.International journal of environmental research and public health · 2023
    Article
  19. Article
  20. Vaping and Mental Health Conditions in Children: An Umbrella Review.Substance abuse : research and treatment · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna TzortziGeorge D. Behrakis Research Lab, Hellenic Cancer Society, 17B Ipitou Street, 10557 Athens, Greece.
Melpo KapetanstratakiGeorge D. Behrakis Research Lab, Hellenic Cancer Society, 17B Ipitou Street, 10557 Athens, Greece.
Vaso EvangelopoulouGeorge D. Behrakis Research Lab, Hellenic Cancer Society, 17B Ipitou Street, 10557 Athens, Greece.
Panagiotis BeghrakisGeorge D. Behrakis Research Lab, Hellenic Cancer Society, 17B Ipitou Street, 10557 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the recent electronic cigarette (e-cigarette) illness outbreak, the current review aimed to collect all related clinical cases for study and analysis and provide a critical synopsis of the proposed injury mechanism. Adhering to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analysis) guidelines, e-cigarette-related clinical cases were identified via Google Scholar and PubMed databases. Additionally, references of published case reports and previous review papers were manually searched, revealing 159 publications presenting e-cigarette-related case reports and 19 reports by the Centers for Disease Control and Prevention. 238 individual cases were identified; 53% traumatic injuries due to e-cigarette explosion or self-combustion, 24% respiratory cases, and 12% poisonings. Additional cases pertained to oral, cardiovascular, immunologic, hematologic, allergic reactions, infant complications, and altered medication levels. Case reports were mainly published between 2016-2019 (78%). The oldest case, a lipoid pneumonia, was published in 2012. The current review showed that e-cigarette-related health effects extend beyond the acute lung injury syndrome, including traumatic, thermal injuries and acute intoxications. Physicians should be aware of the distinct clinical presentations and be trained to respond and treat effectively. Regulators and public health authorities should address the regulatory gap regarding electronic nicotine delivery systems (ENDS) and novel tobacco products.

Indexed as

Electronic Nicotine Delivery SystemsLung InjuryTobacco ProductsVapingAdultFemaleHumansMaleUnited StatesYoung Adulte-cigarette explosionelectronic cigarettee-vaping acute lung injury (EVALI)nicotine intoxicationVAPIvaping

Identifiers

PMID32230711
PMCPMC7177608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.