Evidence map›Paper›PMID 32230708›Full record

ReviewJournal of clinical medicine2020

The Effect of Exercise Training on Brain Structure and Function in Older Adults: A Systematic Review Based on Evidence from Randomized Control Trials.

Feng-Tzu Chen, Rachel J Hopman, Chung-Ju Huang, Chien-Heng Chu, Charles H Hillman, Tsung-Min Hung, Yu-Kai Chang

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 8 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 8 syntheses or guidelines pooled it, 86 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Feng-Tzu ChenGraduate Institute of Sport, Leisure and Hospitality Management, National Taiwan Normal University, Taipei 10610, Taiwan.
Rachel J HopmanDepartment of Psychology, Northeastern University, Boston, MA 02115, USA.
Chung-Ju HuangGraduate Institute of Sport Pedagogy, University of Taipei, Taipei 11153, Taiwan.
Chien-Heng ChuDepartment of Physical Education, National Taiwan Normal University, Taipei 10610, Taiwan.
Charles H HillmanDepartment of Psychology, Northeastern University, Boston, MA 02115, USA.
Tsung-Min HungDepartment of Physical Education, National Taiwan Normal University, Taipei 10610, Taiwan.
Yu-Kai ChangDepartment of Physical Education, National Taiwan Normal University, Taipei 10610, Taiwan.
National Taiwan Normal University · TWNortheastern University · USUniversity of Taipei · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence suggests that exercise training is associated with improvements in brain health in older adults, yet the extant literature is insufficient in detailing why exercise training facilitates brain structure and function. Specifically, few studies have employed the FITT-VP principle (i.e., Frequency, Intensity, Time, Type, Volume, and Progression) to characterize the exercise exposure, thus research is yet to specify which characteristics of exercise training benefit brain outcomes. To determine whether exercise training is consequential to cognitive and brain outcomes, we conducted a systematic review investigating the effects of exercise training on brain structure and function in older adults. PubMed and Scopus were searched from inception to February 2020, and study quality was assessed using the Cochrane risk-of-bias tool. A total of 24 randomized controlled trials were included. This systematic review indicates that older adults involved in exercise training may derive general benefits to brain health, as reflected by intervention-induced changes in brain structure and function. However, such benefits are dependent upon the dose of the exercise intervention. Importantly, current evidence remains limited for applied exercise prescriptions (e.g., volume, progression) and future research is needed to clarify the effects of exercise training on cognitive and brain outcomes in older adults.

Indexed as

aerobic exercise, cognitions, magnetic resonance imaging, aging, grey matter, white matter

Identifiers

PMID32230708
PMCPMC7230405
OpenAlexW3013664738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.