Evidence map›Paper›PMID 32229805›Full record

ArticleRadiation oncology journal2020

Failure patterns of cervical lymph nodes in metastases of unknown origin according to target volume.

Dong-Yun Kim, Dae Seog Heo, Bhumsuk Keam, Chan Young Ock, Soon Hyun Ahn, Ji-Hoon Kim, Kyeong Cheon Jung, Jin Ho Kim, Hong-Gyun Wu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiation oncology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dong-Yun KimDepartment of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea.
Dae Seog HeoDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Bhumsuk KeamDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Chan Young OckDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Soon Hyun AhnDepartment of Otorhinolaryngology, Seoul National University College of Medicine, Seoul, Korea.
Ji-Hoon KimDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Kyeong Cheon JungDepartment of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Jin Ho KimDepartment of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea.
Hong-Gyun WuDepartment of Radiation Oncology, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University · KR

Funding

Ministry of Health and Welfare 1631200
6 · The paper itself

Abstract

purposeThis study was aim to evaluate the patterns of failure according to radiotherapy (RT) target volume for cervical lymph nodes in metastases of unknown primary origin in head and neck region (HNMUO). MATERIALS AND

methodsSixty-two patients with HNMUO between 1998 and 2016 were retrospectively reviewed. We analyzed the clinical outcomes and primary site failure depending on the radiation target volume. The target volume was classified according to whether the potential head and neck mucosal sites were included and whether the neck node was treated involved side only or bilaterally.

resultsPotential mucosal site RT (mucosal RT) was done to 23 patients and 39 patients did not receive mucosal RT. Mucosal RT showed no significant effect on overall survival (OS) and locoregional recurrence (LRR). The location of primary site failure encountered during follow-up period was found to be unpredictable and 75% of patients with recurrence received successful salvage therapies. No significant differences in OS and LRR were found between patients treated to unilateral (n = 35) and bilateral neck irradiation (n = 21). Treatment of both necks resulted in significantly higher mucositis.

conclusionsWe found no advantages in OS and LRR of patients with HNMUO when mucosal sites and bilateral neck node were included in the radiation target volume.

Indexed as

Metastases of unknown primary origin in head and neck regionPattern of failureRadiotherapy

Identifiers

PMID32229805
PMCPMC7113154
OpenAlexW3013413960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.