Evidence map›Paper›PMID 32229570›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Model-based integration of genomics and metabolomics reveals SNP functionality in

Ove Øyås, Sonia Borrell, Andrej Trauner, Michael Zimmermann, Julia Feldmann, Thomas Liphardt, Sebastien Gagneux, Jörg Stelling, Uwe Sauer, Mattia Zampieri

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. In Silico Exploration ofBiomolecules · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Metabolic Versatility ofMetabolites · 2021
    Review
  17. Review
  18. Genetic Diversity inAnnual review of genetics · 2020
    Review
  19. Article
  20. Emerging Evasion Mechanisms of Macrophage Defenses by Pathogenic Bacteria.Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ove ØyåsDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0001-6990-0339
Sonia BorrellDepartment of Medical Parasitoloy and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.
Andrej TraunerDepartment of Medical Parasitoloy and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0002-6260-9829
Michael ZimmermannInstitute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.ORCID 0000-0002-5797-3589
Julia FeldmannDepartment of Medical Parasitoloy and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0001-8389-369X
Thomas LiphardtDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.
Sebastien GagneuxDepartment of Medical Parasitoloy and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0001-7783-9048
Jörg StellingDepartment of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0002-1145-891X
Uwe SauerInstitute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland.
Mattia ZampieriInstitute of Molecular Systems Biology, ETH Zurich, 8093 Zurich, Switzerland zampieri@imsb.biol.ethz.ch.ORCID 0000-0002-9339-068X
Swiss Tropical and Public Health Institute · CHETH Zurich · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human tuberculosis is caused by members of the

Indexed as

Host-Pathogen InteractionsMetabolomePolymorphism, Single NucleotideAminosalicylic AcidAntitubercular AgentsGenome, BacterialGenome-Wide Association StudyGenomicsHumansModels, MolecularMycobacterium tuberculosisPhenotypePhylogenyPyruvate KinaseTuberculosisVirulenceAminosalicylic AcidAntitubercular AgentsPyruvate Kinaseconstraint-based modelmetabolomicstuberculosis

Identifiers

PMID32229570
PMCPMC7165461
OpenAlexW3013455964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.