Evidence map›Paper›PMID 32229519›Full record

ArticleBMJ open2020

Cohort profile: the Brain and Mind Centre

Joanne S Carpenter, Frank Iorfino, Shane Cross, Alissa Nichles, Natalia Zmicerevska, Jacob J Crouse, Jake R Palmer, Alexis E Whitton, Django White, Sharon L Naismith and 5 more

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. The effect of sleep-wake behaviors on the onset of mania in youth: A computational model.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Transdiagnostic Clinical Staging in Youth Mental Health: A primer for clinical practice.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025
    Review
  7. A prognostic model for predicting functional impairment in youth mental health services.European psychiatry : the journal of the Association of European Psychiatrists · 2024
    Article
  8. Observational
  9. Youth Perspectives on 'Highly Personalised and Measurement-Based Care': Qualitative Co-Design of Education Materials.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joanne S CarpenterBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia joanne.carpenter@sydney.edu.au.ORCID 0000-0002-9766-6700
Frank IorfinoBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0003-1109-0972
Shane CrossBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-5413-8342
Alissa NichlesBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Natalia ZmicerevskaBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0001-7649-4711
Jacob J CrouseBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-3805-2936
Jake R PalmerBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0001-8253-0483
Alexis E WhittonBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Django WhiteBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Sharon L NaismithBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Adam J GuastellaBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.
Daniel F HermensBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-8570-2663
Jan ScottBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0002-7203-8601
Elizabeth M ScottBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0003-3907-0324
Ian B HickieBrain & Mind Centre, The University of Sydney, Camperdown, New South Wales, Australia.ORCID 0000-0001-8832-9895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Brain and Mind Centre (BMC)

participantsYoung people (aged 12-30) presenting to clinics coordinated by the BMC were recruited to a research register (n=6743) progressively between June 2008 and July 2018. To date, 2767 individuals have been included in MEASURES: Trained researchers use a clinical research proforma to extract key data from clinical files to detail social and occupational functioning, clinical presentation, self-harm and suicidal thoughts and behaviours, alcohol and other substance use, physical health comorbidities, personal and family history of mental illness, and treatment utilisation at the following time points: baseline, 3, 6, 12, 24, 36, 48, and 60 months, and time last seen. FINDINGS TO DATE: There is moderate to substantial agreement between raters for data collected via the proforma. While wide variations in individual illness course are clear, social and occupational outcomes suggest that the majority of cohort members show no improvement in functioning over time. Differential rates of longitudinal transition are reported between early and late stages of illness, with a number of baseline factors associated with these transitions. Furthermore, there are longitudinal associations between prior suicide attempts and inferior clinical and functional outcomes. FUTURE PLANS: Future reports will detail the longitudinal course of each outcome domain and examine multidirectional relationships between these domains both cross-sectionally and longitudinally, and explore in subsets the associations between detailed neurobiological measures and clinical, social and functional outcomes.

Indexed as

Mental Health ServicesSuicidal IdeationAdolescentAdultBrainChildCohort StudiesCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleSelf-Injurious BehaviorSubstance-Related DisordersSuicide, AttemptedYoung Adultdepression & mood disordersearly interventionyouth

Identifiers

PMID32229519
PMCPMC7170572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.