Evidence map›Paper›PMID 32229491›Full record

ArticleAntimicrobial agents and chemotherapy2020

Proteomic Changes of Klebsiella pneumoniae in Response to Colistin Treatment and

Lang Sun, Pernille Kronholm Rasmussen, Yinlei Bai, Xiulan Chen, Tanxi Cai, Jifeng Wang, Xiaojing Guo, Zhensheng Xie, Xiang Ding, Lili Niu and 4 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Ceftazidime-avibactam based combinations against carbapenemase producingComputational and structural biotechnology journal · 2022
    Article
  17. Article
  18. Article
  19. A Molecular Perspective on Colistin andDiagnostics (Basel, Switzerland) · 2021
    Review
  20. A Bibliometric Meta-Analysis of Colistin Resistance inDiseases (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Lang SunKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.ORCID 0000-0003-2822-4391
Pernille Kronholm RasmussenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Yinlei BaiBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xiulan ChenKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Tanxi CaiKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Jifeng WangKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiaojing GuoKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Zhensheng XieKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xiang DingKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Lili NiuKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Nali ZhuKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xuefu YouBeijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Finn KirpekarDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark f.kir@bmb.sdu.dk fqyang@ibp.ac.cn.
Fuquan YangKey Laboratory of Protein and Peptide Pharmaceuticals and Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China f.kir@bmb.sdu.dk fqyang@ibp.ac.cn.
Chinese Academy of Sciences · CNUniversity of Southern Denmark · DKChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymyxins are increasingly used as the critical last-resort therapeutic options for multidrug-resistant Gram-negative bacteria. Unfortunately, polymyxin resistance has increased gradually over the past few years. Although studies on polymyxin mechanisms are expanding, systemwide analyses of the underlying mechanism for polymyxin resistance and stress response are still lacking. To understand how

Indexed as

ColistinKlebsiella pneumoniaeAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, BacterialMicrobial Sensitivity TestsMutationProteomicsAnti-Bacterial AgentsBacterial ProteinsColistincrrB mutationKlebsiella pneumoniaelipid A modificationmultidrug efflux pump KexDpolymyxin resistanceproteomicsβ-lactamase

Identifiers

PMID32229491
PMCPMC7269499
OpenAlexW3013657292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.