Evidence map›Paper›PMID 32229228›Full record

ArticleChest2020

The Association of ICU Acuity With Adherence to ICU Evidence-Based Processes of Care.

Kelly C Vranas, Jennifer Y Scott, Omar Badawi, Michael O Harhay, Christopher G Slatore, Donald R Sullivan, Meeta Prasad Kerlin

Abstract read
In one paragraph

Article in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Do the Right Thing.Chest · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Kelly C VranasDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research & Development, VA Portland Health Care System, Portland, OR; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA. Electronic address: vranas@ohsu.edu.
Jennifer Y ScottHealth Services Research & Development, VA Portland Health Care System, Portland, OR.
Omar BadawiDepartment of Research and Development, Philips Healthcare, Baltimore, MD; Department of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, MD; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA.
Michael O HarhayDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA; Palliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA.
Christopher G SlatoreDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research & Development, VA Portland Health Care System, Portland, OR.
Donald R SullivanDivision of Pulmonary and Critical Care, Oregon Health & Science University, Portland, OR; Health Services Research & Development, VA Portland Health Care System, Portland, OR.
Meeta Prasad KerlinPalliative and Advanced Illness Research (PAIR) Center, University of Pennsylvania, Philadelphia, PA; Pulmonary, Allergy and Critical Care Division, University of Pennsylvania, Philadelphia, PA.

Funding

Oregon Emergency Care Research Multidisciplinary Training ProgramK12HL133115 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRIS, CYNTHIA D, NEWGARD, CRAIG D. · 2016 to 2020
$2.9M
Impact of Specialist Palliative Care on Outcomes in Advanced Stage Lung CancerK07CA190706 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SULLIVAN, DONALD R · 2015 to 2019
$826k
Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failureR00HL141678 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HARHAY, MICHAEL OSCAR · 2020 to 2022
$747k
Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failureK99HL141678 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HARHAY, MICHAEL OSCAR · 2018 to 2019
$214k
Optimizing Critical Care for Patients with Acute Respiratory Failure: A Mixed-Methods StudyIK2HX003005 · VA · PORTLAND VA MEDICAL CENTER · PI VRANAS, KELLY C. · 2020 to 2023
–
HSRD VA IK2 HX003005NCI NIH HHS K07 CA190706NHLBI NIH HHS K12 HL133115NHLBI NIH HHS K99 HL141678NHLBI NIH HHS R00 HL141678
6 · The paper itself

Abstract

backgroundAdmission to high-acuity ICUs has been associated with improved outcomes compared with outcomes in low-acuity ICUs, although the mechanism for these findings is unclear. RESEARCH QUESTION: The goal of this study was to determine if high-acuity ICUs more effectively implement evidence-based processes of care that have been associated with improved clinical outcomes. STUDY DESIGN AND

methodsThis retrospective cohort study was performed in adult ICU patients admitted to 322 ICUs in 199 hospitals in the Philips ICU telemedicine database between 2010 and 2015. The primary exposure was ICU acuity, defined as the mean Acute Physiology and Chronic Health Evaluation IVa score of all admitted patients in a calendar year, stratified into quartiles. Multivariable logistic regression was used to examine relations of ICU acuity with adherence to evidence-based VTE and stress ulcer prophylaxis, and with the avoidance of potentially harmful events. These events included hypoglycemia, sustained hyperglycemia, and liberal transfusion practices (defined as RBC transfusions prescribed for nonbleeding patients with preceding hemoglobin levels ≥ 7 g/dL).

resultsAmong 1,058,510 ICU admissions, adherence to VTE and stress ulcer prophylaxis was high across acuity levels. In adjusted analyses, those admitted to low-acuity ICUs compared with the highest acuity ICUs were more likely to experience hypoglycemic events (adjusted OR [aOR], 1.12; 95% CI, 1.04-1.19), sustained hyperglycemia (aOR, 1.07; 95% CI, 1.04-1.10), and liberal transfusion practices (aOR, 1.55; 95% CI, 1.33-1.82).

interpretationHigh-acuity ICUs were associated with better adherence to several evidence-based practices, which may be a marker of high-quality care. Future research should investigate how high-acuity ICUs approach ICU organization to identify targets for improving the quality of critical care across all ICU acuity levels.

Indexed as

Critical CareGuideline AdherencePatient AcuityAgedBlood TransfusionFemaleHospital MortalityHumansHyperglycemiaHypoglycemiaMaleMiddle AgedPractice Guidelines as TopicPressure UlcerRetrospective Studiescritical careevidence-based medicineguidelinesICUpatient safety

Identifiers

PMID32229228
PMCPMC7417378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.