Evidence map›Paper›PMID 32228709›Full record

ArticlePediatric rheumatology online journal2020

Inpatient mortality in transition-aged youth with rheumatic disease: an analysis of the National Inpatient Sample.

Paul T Jensen, Keumseok Koh, Rebecca E Cash, Stacy P Ardoin, Ayaz Hyder

Open access · goldAbstract read
In one paragraph

Article in Pediatric rheumatology online journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Paul T JensenIntermountain Healthcare, St. George, USA. Paul.Jensen@imail.org.ORCID https://orcid.org/0000-0002-2522-1382
Keumseok KohUniversity of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0001-7263-2697
Rebecca E CashMassachussetts General Hospital, Boston, USA.ORCID https://orcid.org/0000-0002-0355-1014
Stacy P ArdoinThe Ohio State University and Nationwide Children's Hospital, Columbus, USA.ORCID https://orcid.org/0000-0003-4239-3634
Ayaz HyderThe Ohio State University and Nationwide Children's Hospital, Columbus, USA.ORCID https://orcid.org/0000-0003-4865-6482
Nationwide Children's Hospital · USIntermountain Healthcare · USMassachusetts General Hospital · USUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransition from pediatric to adult care is a vulnerable time for youth with chronic diseases. In youth with rheumatic disease, studies show high rates of loss to follow up and increased disease activity. However, mortality data are lacking. In this study, we assessed whether transitional age is a risk factor for inpatient mortality.

methodsWe analyzed the 2012-2014 National Inpatient Sample database, a representative sample of discharges in the United States. Individuals with rheumatic diseases were identified by International Statistical Classification of Disease - 9 (ICD-9) codes at time of discharge. Youth were categorized into three age groups: pre-transitional (11-17), transitional (18-24) and post transitional (25-31). We fitted univariable and multivariable logistic regression models to assess whether transitional age was a risk factor for inpatient mortality.

resultsThere were 30,269 hospital discharges which met our inclusion criteria of diagnosis and age. There were 195 inpatient deaths (0.7%). The most common causes of death were infection (39.5%), pulmonary disease (13.8%), and cardiac disease (11.2%). The Odds ratio for inpatient mortality of a transitional-aged individual was 1.18 compared to controls (p = 0.3). Black race (OR = 1.4), male sex (OR = 1.75), and a diagnosis of systemic sclerosis (OR = 4.81) or vasculitis (OR = 2.85) were the greatest risk factors of inpatient mortality.

conclusionTransitional age was not a risk factor for inpatient mortality in this study. We did identify other risk factors other than age. Further studies are required to assess if there is an increased risk of mortality in outpatients of the transitional age group.

Indexed as

Hospital MortalityTransition to Adult CareAdolescentAdultAge FactorsArthritis, RheumatoidBlack or African AmericanCause of DeathChildFemaleHeart DiseasesHumansInfectionsLogistic ModelsLung DiseasesLupus Erythematosus, SystemicPediatric rheumatologyTransition to adult care

Identifiers

PMID32228709
PMCPMC7106859
OpenAlexW3013207307

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.