Evidence map›Paper›PMID 32228632›Full record

ArticleJournal of cardiothoracic surgery2020

Removal of tumor thrombus from the azygos vein in an esophageal squamous cell carcinoma patient.

Qijue Lu, Bowen Shi, Jiang Hong, Hezhong Chen, Chunguang Li

Abstract readCase Reports
In one paragraph

Article in Journal of cardiothoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Qijue LuDepartment of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Bowen ShiDepartment of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Jiang HongDepartment of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Hezhong ChenDepartment of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Chunguang LiDepartment of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China. dr_lichunguang@sina.com.

Funding

National Natural Science Foundation of China 81472688
6 · The paper itself

Abstract

backgroundEsophageal squamous cell carcinoma with tumor thrombus in the arch of the azygos vein has not been reported to date. Neoadjuvant chemotherapy can decrease the stage in patients with advanced preoperative tumor staging, regaining surgical opportunities and significantly prolonging progression-free survival and overall survival. Herein, we present a case of esophageal squamous cell carcinoma accompanied by tumor thrombus in the arch of the azygos vein, and the patient underwent radical surgery after neoadjuvant chemotherapy. CASE PRESENTATION: A 63-year-old male with esophageal squamous cell carcinoma was found to have tumor thrombus formation in the arch of the azygos vein. Four courses of neoadjuvant chemotherapy with the TP regimen (paclitaxel plus nedaplatin) were given. Reexamination revealed a significant reduction in tumor and tumor thrombus volume. Therefore, McKeown radical resection for esophageal cancer and removal of the tumor thrombus in the arch of the azygos vein were performed. Postoperative pathology suggested complete remission of the esophageal tumor and the presence of small focal cancer tissues in the arch of the azygos vein.

conclusionWe report a case of esophageal squamous cell carcinoma with tumor thrombus formation in the azygos vein. We conducted radical resection after 4 rounds of neoadjuvant chemotherapy, and the pathological results revealed complete remission of the tumor. We report our experience addressing this rare case, and we hope to find the underlying mechanism of tumor thrombus formation and whether it has any effects on prognosis in our future study.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsAzygos VeinChemotherapy, AdjuvantEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagectomyHumansMaleMiddle AgedNeoadjuvant TherapyNeoplasm StagingOrganoplatinum CompoundsPaclitaxelThrombosisnedaplatinOrganoplatinum CompoundsPaclitaxelAzygos veinEsophageal squamous cell carcinomaNeoadjuvant chemotherapyTumor thrombus

Identifiers

PMID32228632
PMCPMC7104544

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.