ArticleHealth and quality of life outcomes2020
Health related quality of life and healthcare utilization among adults with diabetes and kidney and eye complications in the United States.
Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Impact of chronic kidney disease on adults and their caregivers in the United States: a systematic literature review.BMC nephrology · 2026Pooled it
- Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Article
- Clinical, humanistic, and economic burden of sickle cell disease in The Jazan Region, Saudi Arabia.PloS one · 2026Observational
- Predicting Health-Related Quality of Life Using Social Determinants of Health: A Machine Learning Approach with the All of Us Cohort.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- Risk factors for diabetes in recently arrived migrants in Scania, Sweden compared to the general population.Frontiers in public health · 2025Article
- Factors Influencing Kidney Transplantation Experiences for Patients From Culturally and Linguistically Diverse Backgrounds: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Health-Related Quality of Life and Healthcare Events in Patients with Monotherapy of Anti-Diabetes Medications.Healthcare (Basel, Switzerland) · 2023Article
- Is it time to consider depression as a major complication of type 2 diabetes? Evidence from a large population-based cohort study.Acta diabetologica · 2022Article
- Noninfectious Intermediate, Posterior, or Panuveitis: Results from the Retrospective, Observational, International EyeCOPE Study.Ophthalmology and therapy · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne-third of adults with diabetes in the United States have chronic kidney disease (CKD), and 19% of them have eye complications (ECs). However, little is known about the Health-related Quality of Life (HRQoL) of adults with both of these diabetes-related complications. Therefore, the purpose of this study is to examine differences in the HRQoL, mental health, and healthcare utilization of adults with diabetes who have CKD, ECs, both or neither.
methodsA cross-sectional study design was implemented using data from multiple panels (2009-2015) of the Medical Expenditure Panel Survey. HRQoL was measured using the SF-12 Physical and Mental Component Summary (PCS & MCS) scores. The HRQoL, mental health, and healthcare utilization of four mutually exclusive groups: 1) diabetes with both CKD and ECs; 2) diabetes with CKD only; 3) diabetes with ECs only, and 4) diabetes with neither CKD nor ECs were compared. In all analyses, adults with neither CKD nor ECs were the reference group.
resultsThere were 8415 adults with diabetes who met the inclusion criteria. Approximately, 75% of the study sample had neither CKD nor ECs, 13.3% had ECs only, 5.7% had CKD only, and 5.5% had both CKD and ECs. In the adjusted analyses, adults with both CKD and/or ECs complications exhibited significantly lower HRQoL compared to those with neither CKD nor ECs. Mental illness and psychological distress were higher among adults with both CKD and ECs compared to those with neither CKD nor ECs. Furthermore, adults with CKD and/or ECs had higher polypharmacy, inpatient and emergency services use compared to those with neither CKD nor ECs.
conclusionsThe results indicate that the presence of both CKD and/or ECs was negatively associated with poor HRQoL, poor mental health, higher psychological distress and healthcare utilization in adults with diabetes. The findings emphasize the need for routine assessment and treatment for diabetes-related CKD and/or ECs complications to improve the quality of care for individuals with diabetes.
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