Evidence map›Paper›PMID 32228552›Full record

ArticleBMC urology2020

Clinical efficacy of submucosal injection of triamcinolone acetonide in the treatment of type II/III interstitial cystitis/bladder pain syndrome.

Tao Jiang, Xiaozhou Zhou, Zhipeng Chen, Tailin Xiong, Jian Fu, Zhengchao Liu, Dishi Yan, Zhansong Zhou, Wenhao Shen

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tao JiangDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Xiaozhou ZhouDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Zhipeng ChenDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Tailin XiongDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Jian FuDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Zhengchao LiuDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Dishi YanDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Zhansong ZhouDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China.
Wenhao ShenDepartment of Urology, Urology Institute of PLA, Southwest Hospital, Third Military Medical University (Army Medical University), Gao Tanyan Street 29#, Sha Pingba, Chongqing, 400038, China. chongqingswh@aliyun.com.
Army Medical University · CNSouthwest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the efficacy of submucosal injection of triamcinolone acetonide for the treatment of type II/III interstitial cystitis/bladder pain syndrome.

methodsA retrospective analysis of the clinical data of type II/III interstitial cystitis/bladder pain syndrome patients treated in our department from April 2016 to August 2018 was conducted, and changes in International Prostate Symptom Scores and the Pelvic Pain and Urgency/Frequency symptom scale after surgery were evaluated to explore factors that may affect patient outcomes.

resultsA total of 27 female patients and 8 male patients were enrolled, with type II patients accounting for 62.9% of the sample, and the median follow-up duration was 31 months (range: 12-40 months). Twenty-two patients (74.3%) had significantly improved questionnaire scores at 4 weeks postoperatively. Treatment efficacy was sustained for at least 1 year in 15 patients, and persistent effectiveness was noted in 10 (28.6%) patients. Patients with an advanced age (p = 0.015), high pain scores (p = 0.040), and higher International Prostate Symptom Scores (p = 0.037) and Pelvic Pain and Urgency/Frequency symptom scale scores (p = 0.020) were more likely to benefit from submucosal injection of triamcinolone acetonide. Gender, disease duration, and the presence of Hunner's lesions had no predictive value for treatment outcomes.

conclusionSubmucosal injection of triamcinolone acetonide can improve the clinical symptoms and quality of life in both men and women with type II/III interstitial cystitis/bladder pain syndrome. Patients with an advanced age and more severe interstitial cystitis/bladder pain syndrome related symptoms may benefit more from triamcinolone acetonide injection.

Indexed as

AdultAgedAged, 80 and overAnti-Inflammatory AgentsCystitis, InterstitialCystoscopyFemaleHumansInjectionsMaleMiddle AgedMucous MembraneRetrospective StudiesTreatment OutcomeTriamcinolone AcetonideAnti-Inflammatory AgentsTriamcinolone AcetonideBladder pain syndromeHunner’s lesionInterstitial cystitisTriamcinolone

Identifiers

PMID32228552
PMCPMC7106786
OpenAlexW3013814292

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.