ArticleBMC microbiology2020
The molecular characters and antibiotic resistance of Clostridioides difficile from economic animals in China.
Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Comparison of Phenotypic and Genotypic Antimicrobial Resistances in BovineAntibiotics (Basel, Switzerland) · 2026Article
- Molecular epidemiology and antimicrobial resistance profiles ofFrontiers in microbiology · 2026Article
- Genomic analysis of a novel ST11(PR34365)Open life sciences · 2025Article
- Antimicrobial resistance ofOne health (Amsterdam, Netherlands) · 2024Article
- Recent development and fighting strategies for lincosamide antibiotic resistance.Clinical microbiology reviews · 2024Review
- [Analysis ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Usefulness of Capillary Gel Electrophoresis-Based PCR for Detection ofGels (Basel, Switzerland) · 2024Article
- Genetic marker: a genome mapping tool to decode genetic diversity of livestock animals.Frontiers in genetics · 2024Review
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- Make It LessGenes · 2022Review
- Genotyping and Antimicrobial Susceptibility ofPathogens (Basel, Switzerland) · 2021Article
- Comparative genomic and transmission analysis ofEmerging microbes & infections · 2021Article
- Article
- The Colonisation of Calves in Czech Large-Scale Dairy Farms by Clonally-RelatedMicroorganisms · 2020Article
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10 authors.
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Abstract
backgroundIt has been performed worldwidely to explore the potential of animals that might be a reservoir for community associated human infections of Clostridioides difficile. Several genetically undistinguished PCR ribotypes of C. difficile from animals and human have been reported, illustrating potential transmission of C. difficile between them. Pig and calf were considered as the main origins of C. difficile with predominant RT078 and RT033, respectively. As more investigations involved, great diversity of molecular types from pig and calf were reported in Europe, North American and Australia. However, there were quite limited research on C. difficile isolates from meat animals in China, leading to non-comprehensive understanding of molecular epidemiology of C. difficile in China.
resultsA total of 55 C. difficile were isolated from 953 animal stool samples, within which 51 strains were from newborn dairy calf less than 7 days in Shandong Province. These isolates were divided into 3 STs and 6 RTs, of which ST11/RT126 was predominant type, and responsible for majority antibiotic resistance isolates. All the isolates were resistant to at least one tested antibiotics, however, only two multidrug resistant (MDR) isolates were identified. Furthermore, erythromycin (ERY) and clindamycin (CLI) were the two main resistant antibiotics. None of the isolates were resistant to vancomycin (VAN), metronidazole (MTZ), tetracycline (TET), and rifampin (RIF).
conclusionsIn this study, we analyzed the prevalence, molecular characters and antibiotic resistance of C. difficile from calf, sheep, chicken, and pig in China. Some unique features were found here: first, RT126 not RT078 were the dominant type from baby calf, and none isolates were got from pig; second, on the whole, isolates from animals display relative lower resistant rate to these 11 tested antibiotics, compared with isolates from human in China in our previous report. Our study helps to deep understanding the situation of C. difficile from economic animals in China, and to further study the potential transmission of C. difficile between meat animals and human.
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