Evidence map›Paper›PMID 32228178›Full record

ArticleThyroid : official journal of the American Thyroid Association2020

Characterization of Allele-Specific Regulation of Telomerase Reverse Transcriptase in Promoter Mutant Thyroid Cancer Cell Lines.

Brittany A McKelvey, Timothy Gilpatrick, Yongchun Wang, Winston Timp, Christopher B Umbricht, Martha A Zeiger

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

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  11. InTERTwined: howCurrent opinion in endocrine and metabolic research · 2023
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  20. TERT-Regulation and Roles in Cancer Formation.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brittany A McKelveyDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Timothy GilpatrickDepartment of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yongchun WangDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Winston TimpDepartment of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Christopher B UmbrichtDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Martha A ZeigerSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Johns Hopkins University · USNational Institutes of Health · US

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
Training and Development of Outstanding Surgeon ScientistsZIEBC011992 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ZEIGER, MARTHA · 2020 to 2024
$9.6M
Nanopore based profiling of epigenetic stateR01HG009190 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI TIMP, WINSTON GEORGE · 2017 to 2024
$4.8M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesGene Expression Regulation, NeoplasticPromoter Regions, GeneticCell Line, TumorChromatinCpG IslandsCRISPR-Associated Protein 9DNA, ComplementaryDNA MethylationGA-Binding Protein Transcription FactorHeterozygoteHistonesHumansImmunoprecipitationMutationPolymorphism, Single NucleotideChromatinCRISPR-Associated Protein 9DNA, ComplementaryGA-Binding Protein Transcription FactorGABPA protein, humanhistone H3 trimethyl Lys4HistonesMYC protein, humanProto-Oncogene Proteins c-mycTelomeraseTERT protein, humanTranscription Factorsallele specificityDNA methylationtelomerasetranscriptional regulation

Identifiers

PMID32228178
PMCPMC7583328
OpenAlexW3012957965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.