Evidence map›Paper›PMID 32227948›Full record

ArticleJournal of medicinal chemistry2020

Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases.

Mohamed A Seleem, Nathalia Rodrigues de Almeida, Yashpal Singh Chhonker, Daryl J Murry, Zaira da Rosa Guterres, Amanda M Blocker, Shiomi Kuwabara, Derek J Fisher, Emilse S Leal, Manuela R Martinefski and 4 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. ACS infectious diseases · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Mohamed A SeleemDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.ORCID 0000-0003-4379-5133
Nathalia Rodrigues de AlmeidaDepartment of Chemistry, College of Arts and Sciences, University of Nebraska at Omaha, Omaha, Nebraska 68182, United States.ORCID 0000-0002-9552-1233
Yashpal Singh ChhonkerClinical Pharmacology Laboratory, Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.ORCID 0000-0001-6455-5388
Daryl J MurryClinical Pharmacology Laboratory, Department of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.ORCID 0000-0002-4169-5027
Zaira da Rosa GuterresLaboratory of Cytogenetics and Mutagenesis, State University of Mato Grosso do Sul, Mundo Novo, Matto Grasso do Sul, Brazil.
Amanda M BlockerSchool of Biological Sciences, Southern Illinois University Carbondale, Carbondale, Illinois 62901, United States.
Shiomi KuwabaraSchool of Biological Sciences, Southern Illinois University Carbondale, Carbondale, Illinois 62901, United States.
Derek J FisherSchool of Biological Sciences, Southern Illinois University Carbondale, Carbondale, Illinois 62901, United States.ORCID 0000-0002-1663-8389
Emilse S LealCentro de Investigaciones en BioNanociencias (CIBION), Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Godoy Cruz, 2390 Ciudad de Buenos Aires, Argentina.
Manuela R MartinefskiCentro de Investigaciones en BioNanociencias (CIBION), Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Godoy Cruz, 2390 Ciudad de Buenos Aires, Argentina.ORCID 0000-0002-4501-3783
Mariela BolliniCentro de Investigaciones en BioNanociencias (CIBION), Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Godoy Cruz, 2390 Ciudad de Buenos Aires, Argentina.ORCID 0000-0002-8718-6236
María Eugenia MongeCentro de Investigaciones en BioNanociencias (CIBION), Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Godoy Cruz, 2390 Ciudad de Buenos Aires, Argentina.ORCID 0000-0001-6517-5301
Scot P OuelletteDepartment of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Martin Conda-SheridanDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.ORCID 0000-0002-3568-2545
Consejo Nacional de Investigaciones Científicas y Técnicas · ARSouthern Illinois University Carbondale · USUniversity of Nebraska Medical Center · USNebraska Medical Center · USUniversidade Estadual de Mato Grosso do Sul · BRUniversity of Nebraska at Omaha · US

Funding

Target Validation CoreP20GM121316 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ADRIAN R BLACK · 2018 to 2026
$23.5M
NIGMS NIH HHS P20 GM121316
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell SurvivalChlamydia trachomatisChlorobenzenesDose-Response Relationship, DrugDrosophila melanogasterHeLa CellsHumansMicePeptide HydrolasesProtease InhibitorsPyridineschlorobenzeneChlorobenzenesPeptide HydrolasesProtease InhibitorsPyridines

Identifiers

PMID32227948
PMCPMC10353488
OpenAlexW3013931554

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.