Evidence map›Paper›PMID 32227939›Full record

ArticleJournal of the American Chemical Society2020

Cellular Force Nanoscopy with 50 nm Resolution Based on Integrin Molecular Tension Imaging and Localization.

Yuanchang Zhao, Kaushik Pal, Ying Tu, Xuefeng Wang

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  20. Recent Advances in Cell Adhesive Force Microscopy.Sensors (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuanchang ZhaoDepartment of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0003-1458-5321
Kaushik PalDepartment of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, United States.
Ying TuDepartment of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0001-7770-9876
Xuefeng WangDepartment of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0002-3301-3196

Funding

Study the role of integrin tension in cell migration, platelet functions and phagocytosisR35GM128747 · NIGMS · UNIVERSITY OF CINCINNATI · PI Xuefeng Wang · 2018 to 2026
$2.8M
NIGMS NIH HHS R35 GM128747
6 · The paper itself

Abstract

Integrin-transmitted cellular forces have rich spatial dynamics and are vital to many cellular functions. To advance the sensitivity and spatial resolution of cellular force imaging, we developed a force-activatable emitter reporting single-molecular tension events and the associated cellular force nanoscopy (CFN). Immobilized on a surface, the emitters are initially dark (>99.8% quenched), providing a low fluorescence background despite the high coating density (>2000/μm

Indexed as

Biomechanical PhenomenaHumansIntegrinsIntegrins

Identifiers

PMID32227939
PMCPMC7337222

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.