Evidence map›Paper›PMID 32227523›Full record

ArticleMicrobiology and immunology2020

Expression of small RNAs of Bordetella pertussis colonizing murine tracheas.

Yukihiro Hiramatsu, Koichiro Suzuki, Daisuke Motooka, Shota Nakamura, Yasuhiko Horiguchi

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Conquering the host:Frontiers in microbiology · 2022
    Review
  6. Article
  7. Melanin Produced bymSphere · 2021
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yukihiro HiramatsuDepartment of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-6340-864X
Koichiro SuzukiDepartment of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Daisuke MotookaDepartment of Infection Metagenomics, Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Shota NakamuraDepartment of Infection Metagenomics, Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Yasuhiko HoriguchiDepartment of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.ORCID http://orcid.org/0000-0002-1592-5861
The University of Osaka · JPKyoto Biken Laboratories (Japan) · JP

Funding

Japan Society for the Promotion of Science 17H04075Japan Society for the Promotion of Science 19K16638Japan Society for the Promotion of Science 19K23845JSPS KAKENHI
6 · The paper itself

Abstract

We performed RNA sequencing on Bordetella pertussis, the causative agent of whooping cough, and identified nine novel small RNAs (sRNAs) that were transcribed during the bacterial colonization of murine tracheas. Among them, four sRNAs were more strongly expressed in vivo than in vitro. Moreover, the expression of eight sRNAs was not regulated by the BvgAS two-component system, which is the master regulator for the expression of genes contributing to the bacterial infection. The present results suggest a BvgAS-independent gene regulatory system involving the sRNAs that is active during B. pertussis infection.

Indexed as

Bordetella pertussisAnimalsBacterial ProteinsGene Expression Regulation, BacterialGenes, RegulatorMaleMiceMice, Inbred C57BLRNA, BacterialRNA, Small UntranslatedTracheaTranscription FactorsVirulenceVirulence Factors, BordetellaWhooping CoughBacterial ProteinsRNA, BacterialRNA, Small UntranslatedTranscription FactorsVirulence Factors, BordetellaBordetella pertussisBvgASgene regulatory systemin vivo RNA sequencingsmall RNA

Identifiers

PMID32227523
PMCPMC7317797
OpenAlexW3013326807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.