Evidence map›Paper›PMID 32227382›Full record

ArticlePsycho-oncology2020

Spirituality in cancer patients on phase 1 clinical trials.

Betty Ferrell, Vincent Chung, Marianna Koczywas, Tami Borneman, Terry L Irish, Nora H Ruel, Nilofer S Azad, Rhonda S Cooper, Thomas J Smith

Open access · greenAbstract readClinical Trial, Phase I
In one paragraph

Article in Psycho-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Use of supportive care services and advance care planning among early phase oncology clinical trial participants.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Betty FerrellDivision of Nursing Research and Education, City of Hope National Medical Center, Duarte, California, USA.ORCID 0000-0003-0061-5235
Vincent ChungDepartment of Oncology, City of Hope National Medical Center, Duarte, California, USA.
Marianna KoczywasDepartment of Oncology, City of Hope National Medical Center, Duarte, California, USA.
Tami BornemanDivision of Nursing Research and Education, City of Hope National Medical Center, Duarte, California, USA.
Terry L IrishCity of Hope National Medical Center, Duarte, California, USA.
Nora H RuelBeckman Research Institute, City of Hope National Medical Center, Duarte, California, USA.
Nilofer S AzadJohns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
Rhonda S CooperChaplain of the Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
Thomas J SmithJohns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
City Of Hope National Medical Center · USSidney Kimmel Comprehensive Cancer Center · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Integration of Palliative Care for Cancer Patients on Phase I TrialsR01CA177562 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI FERRELL, BETTY R · 2014 to 2018
$6.8M
NCI NIH HHS City of Hope Core, NCI P30CA033572NCI NIH HHS NCI-R01 CA177562NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA177562
6 · The paper itself

Abstract

objectivesPatients with cancer who are at a transition to Phase I investigational treatments have been identified as an underserved population with regard to palliative care. This disease transition is often accompanied by spiritual and existential concerns. The study objective was to conduct a secondary analysis of data from a larger study testing a palliative care intervention. This paper reports the findings of this secondary focus on the spiritual needs of this population.

methodsPatients (n = 479) were accrued to this study prior to initiating a Phase I clinical trial with data collected at baseline, and 4, 12, and 24 week follow-up.

resultsQualitative data revealed that the transition to Phase 1 trial participation is a time of balancing hope for extended life with the reality of advancing disease. Quantitative results demonstrated increased spirituality over time in both religious- and non-religious-affiliated patients.

conclusionsPatients entering Phase I trials have important spiritual needs as they face treatment decisions, advancing disease, and often mortality. Spiritual care should be provided to seriously ill patients as a component of quality care.

Indexed as

SpiritualityAdaptation, PsychologicalAdultExistentialismFemaleHopeHumansMaleMiddle AgedNeoplasmsPalliative CareQuality of LifeSpiritual TherapiesTerminally Illcancercancer patientsexistential concernshopeinvestigational treatmentsoncologyspiritual carespiritualityunderserved populations

Identifiers

PMID32227382
PMCPMC9094428
OpenAlexW3013180845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.