Evidence map›Paper›PMID 32227380›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Gold-Catalyzed Cycloisomerization of Sulfur Ylides to Dihydrobenzothiepines.

Christian Knittl-Frank, Iakovos Saridakis, Thomas Stephens, Rafael Gomes, James Neuhaus, Antonio Misale, Rik Oost, Alberto Oppedisano, Nuno Maulide

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Gold-Catalyzed Cycloisomerization of Sulfur Ylides to Dihydrobenzothiepines.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian Knittl-FrankInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0001-9167-5414
Iakovos SaridakisInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0002-2690-5401
Thomas StephensInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Rafael GomesInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0002-2598-8540
James NeuhausInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Antonio MisaleInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Rik OostInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
Alberto OppedisanoInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0002-5791-7341
Nuno MaulideInstitute for organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0003-3643-0718

Funding

Austrian Science Fund W1232Austrian Science Fund FWF W 1232FP7 Ideas: European Research Council FLATOUTH2020 European Research Council 682002 VINCATSocrates Erasmus Program Grant
6 · The paper itself

Abstract

The metal-promoted nucleophilic addition of sulfur ylides to π-systems is a well-established reactivity. However, the driving force of such transformations, elimination of a sulfide moiety, entails stoichiometric byproducts making them unfavorable in terms of atom economy. In this work, a new take on sulfur ylide chemistry is reported, an atom-economical gold(I)-catalyzed synthesis of dihydrobenzo[b]thiepines. The reaction proceeds under mild conditions at room temperature.

Indexed as

alkynesbenzothiepinesgoldrearrangementsulfonium ylides

Identifiers

PMID32227380
PMCPMC7496544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.