Evidence map›Paper›PMID 32227368›Full record

Trial reportThe International journal of eating disorders2020

Weight suppression and weight maintenance following treatment of anorexia nervosa.

Blair Uniacke, Evelyn Attia, Allan Kaplan, B Timothy Walsh

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Blair UniackeDepartment of Psychiatry, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0002-8858-3575
Evelyn AttiaDepartment of Psychiatry, Columbia University Irving Medical Center, New York, New York, USA.
Allan KaplanDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-5077-2787
B Timothy WalshDepartment of Psychiatry, Columbia University Irving Medical Center, New York, New York, USA.
Columbia University Irving Medical Center · USUniversity of Toronto · CA

Funding

Research Training in Biobehavioral Disturbances of Eating DisordersT32MH096679 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EVELYN ATTIA, B. TIMOTHY WALSH · 2013 to 2026
$2.4M
FLUOXETINE AFTER WEIGHT RESTORATION IN ANOREXIA NERVOSAR01MH060271 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI WALSH, B. TIMOTHY · 2000 to 2004
$1.5M
FLUOXETINE AFTER WEIGHT RESTORATION IN ANOREXIA NERVOSAR01MH060336 · NIMH · UHN TORONTO GENERAL HOSPITAL · PI KAPLAN, ALLAN S · 2000 to 2003
$875k
NIMH NIH HHS R01 MH060271NIMH NIH HHS R01 MH060336NIMH NIH HHS T32 MH096679
6 · The paper itself

Abstract

objectiveThe value of weight suppression (WS) in predicting the course of anorexia nervosa (AN) is uncertain. The objective of this study was to determine, using data from a previously published study, whether patients who remain weight suppressed following restoration to a minimally normal weight are at greater risk for relapse.

methodFollowing weight restoration, 93 women with AN were randomly assigned to receive fluoxetine or placebo along with cognitive behavioral therapy for 1 year. WS (highest adult weight minus current weight), body mass index (BMI), and their interaction were assessed as predictors of change in weight over the first 28 days, of successful weight maintenance at 6 and 12 months, and of time to relapse.

resultsNeither WS nor its interaction with BMI predicted successful weight maintenance at 6 and 12 months, time to relapse, or weight change over the first 28 days following discharge. DISCUSSION: This study found that WS does not substantially impact the likelihood of successful weight maintenance or time to relapse following restoration to a minimally normal weight in AN.

Indexed as

Anorexia NervosaBody Weight MaintenanceFemaleHumansanorexia nervosaeating disordersoutcomerelapseweight suppression

Identifiers

PMID32227368
PMCPMC7584398
OpenAlexW3013773330

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.