ArticlePsychophysiology2020
Interplay between components of pupil-linked phasic arousal and its role in driving behavioral choice in Go/No-Go perceptual decision-making.
Article in Psychophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pupil Reactions to Tactile Stimulation: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- Article
- Phasic and tonic arousal distinctly shape human decision bias.Communications biology · 2026Article
- The Contribution of the Locus Ceruleus-Norepinephrine System to the Coupling between Pupil-Linked Arousal and Cortical State.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Behavioral state-dependent norepinephrine dynamics in the primary somatosensory and prefrontal cortices during tactile detection tasks.bioRxiv : the preprint server for biology · 2026Article
- Catecholamines reduce choice history biases in perceptual decision making.PLoS biology · 2025Article
- Phase synchrony between prefrontal noradrenergic and cholinergic signals indexes inhibitory control.Nature communications · 2025Article
- Task-irrelevant stimuli reliably boost phasic pupil-linked arousal but do not affect decision formation.Scientific reports · 2024Article
- Optogenetic Locus Coeruleus Stimulation Improves Pupil Size Tracking of Cortical State.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024Article
- Optimization of Temporal Coding of Tactile Information in Rat Thalamus by Locus Coeruleus Activation.Biology · 2024Article
- Recent trends in multiple metrics and multimodal analysis for neural activity and pupillometry.Frontiers in neurology · 2024Article
- Adaptive decision-making depends on pupil-linked arousal in rats performing tactile discrimination tasks.Journal of neurophysiology · 2023Article
- Review
- The Neuromodulatory Role of the Noradrenergic and Cholinergic Systems and Their Interplay in Cognitive Functions: A Focused Review.Brain sciences · 2022Review
- Article
- Rapid Effects of Vagus Nerve Stimulation on Sensory Processing Through Activation of Neuromodulatory Systems.Frontiers in neuroscience · 2022Review
- A practical introduction to using the drift diffusion model of decision-making in cognitive psychology, neuroscience, and health sciences.Frontiers in psychology · 2022Review
- Increasing pupil size is associated with improved detection performance in the periphery.Attention, perception & psychophysics · 2022Article
- Article
- Pupil-linked phasic arousal predicts a reduction of choice bias across species and decision domains.eLife · 2020Article
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4 authors.
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Abstract
In decision-making tasks, neural circuits involved in different aspects of information processing may activate the central arousal system, likely through their interconnection with brainstem arousal nuclei, collectively contributing to the observed pupil-linked phasic arousal. However, the individual components of the phasic arousal associated with different elements of information processing and their effects on behavior remain little known. In this study, we used machine learning techniques to decompose pupil-linked phasic arousal evoked by different components of information processing in rats performing a Go/No-Go perceptual decision-making task. We found that phasic arousal evoked by stimulus encoding was larger for the Go stimulus than the No-Go stimulus. For each session, the separation between distributions of phasic arousal evoked by the Go and by the No-Go stimulus was predictive of perceptual performance. The separation between distributions of decision-formation-evoked arousal on correct and incorrect trials was correlated with decision criterion but not perceptual performance. When a Go stimulus was presented, the action of go was primarily determined by the phasic arousal evoked by stimulus encoding. On the contrary, when a No-Go stimulus was presented, the action of go was determined by phasic arousal elicited by both stimulus encoding and decision formation. Drift diffusion modeling revealed that the four model parameters were better accounted for when phasic arousal elicited by both stimulus encoding and decision formation was considered. These results suggest that the interplay between phasic arousal evoked by both stimulus encoding and decision formation has important functional consequences on forming behavioral choice in perceptual decision-making.
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