Evidence map›Paper›PMID 32227310›Full record

ArticleCVIR endovascular2020

Flow diversion in challenging vascular anatomies: the use of low profile stent retrievers for safe and accurate positioning of the microcatheter.

Ulf Quäschling, Monika Kläver, Cindy Richter, Gordian Hamerla, Simone Mucha, Cordula Scherlach, Jens Maybaum, Karl-Titus Hoffmann, Stefan Schob

Open access · goldAbstract read
In one paragraph

Article in CVIR endovascular, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. First-in-human trial of Center Wire for neuroendovascular therapy to avoid guidewire-related complications.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  8. A novel intracranial exchange guidewire improves the navigation of various endovascular devices: An in vitro study of challenging situations.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  9. Article
  10. The p48 flow diverter: First clinical results in 25 aneurysms in three centers.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ulf QuäschlingDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Monika KläverDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Cindy RichterDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Gordian HamerlaDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Simone MuchaDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Cordula ScherlachDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Jens MaybaumDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Karl-Titus HoffmannDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.
Stefan SchobDepartment for Neuroradiology, University Hospital Leipzig, Liebigstraße 20, 04103, Leipzig, Germany. Stefan.Schob@Medizin.Uni-Leipzig.de.ORCID http://orcid.org/0000-0003-2846-5443
University Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodynamic therapy with Flow-Diverters has become a fundamental option for treatment of cerebral aneurysms. A major obstacle of Flow-Diverters is the comparatively stiff microcatheter required for implantation. Consequentially, maneuverability is limited and primary catheterization of peripheral targets may be difficult or even futile in challenging vascular anatomies. To overcome this, a highly navigable microcatheter must be used to attain the desired vascular segment, followed by a hardly controllable exchange-maneuver via a long microwire, involving a high risk for wire-perforation. Our study aimed to investigate the value of low-profile stent-retrievers as a railway for introduction of the required microcatheter, which allows to maintain a stable endovascular position and reduce the risk for procedural vessel injury.

methods14cases (8females, mean-age 59y) of Flow-Diverter-Implantation requiring the use of a low-profile stent-retriever were reviewed. All cases featured a challenging vascular anatomy. After micro-catheterization of the desired segment, the stent-retriever was carefully deployed as an anchor in a secure, distal location. In all cases a pREset/LITE-stent-retriever was used for introduction of the equipment required for implantation.

resultsIn all cases the anchoring-maneuver was performed without technical complications. The stent-retrievers maintained a stable position after deployment in all situations. No potential traumatic sudden movements of the microcatheter occurred. No procedure-related perforations, dissections or vasospasms were observable during the interventions or their aftermath.

conclusionsIn our experience the stent-retriever-anchoring-maneuver represents a potentially essential and safe amendment for flow diverter treatment in technically challenging situations.

Indexed as

Aneurysm treatmentDifficult endovascular accessExchange maneuverFlow diversionStent retriever

Identifiers

PMID32227310
PMCPMC7103572
OpenAlexW3013701046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.