Evidence map›Paper›PMID 32226942›Full record

ReviewNeuro-oncology advances

Bhuvic Patel, Rukayat Taiwo, Albert H Kim, Gavin P Dunn

Open access · goldAbstract readReview
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Prevalence ofCurrent issues in molecular biology · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Research progress in molecular pathology markers in medulloblastoma.Exploration of targeted anti-tumor therapy · 2023
    Review
  17. Article
  18. Article
  19. The Role of Novel Bladder Cancer Diagnostic and Surveillance Biomarkers-What Should a Urologist Really Know?International journal of environmental research and public health · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bhuvic PatelDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-8062-7310
Rukayat TaiwoDepartment of Neurological Surgery, Stanford University, Stanford, California, USA.
Albert H KimDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Gavin P DunnDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Neurological Surgery · US

Funding

Targeting Neoantigens in GlioblastomaR01NS112712 · NINDS · WASHINGTON UNIVERSITY · PI DUNN, GAVIN PETER · 2019 to 2024
$2.3M
WASHINGTON UNIVERSITY NEUROSURGERY RESIDENT RESEARCH EDUCATION PROGRAMR25NS090978 · NINDS · WASHINGTON UNIVERSITY · PI ZIPFEL, GREGORY J · 2015 to 2023
$2.1M
IMMUNOBIOLOGY OF MALIGNANT GLIOMAK08NS092912 · NINDS · WASHINGTON UNIVERSITY · PI DUNN, GAVIN PETER · 2015 to 2019
$877k
NINDS NIH HHS K08 NS092912NINDS NIH HHS R01 NS112712NINDS NIH HHS R25 NS090978
6 · The paper itself

Abstract

As cells replicate their DNA during mitosis, telomeres are shortened due to the inherent limitations of the DNA replication process. Maintenance of telomere length is critical for cancer cells to overcome cellular senescence induced by telomere shortening. Telomerase reverse transcriptase (TERT) is the rate-limiting catalytic subunit of telomerase, an RNA-dependent DNA polymerase that lengthens telomeric DNA to maintain telomere homeostasis.

Indexed as

central nervous system tumorstelomerase promoter mutationsTERT

Identifiers

PMID32226942
PMCPMC7086299
OpenAlexW3007513193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.