ReviewJournal of pharmaceutical investigation2016
Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems.
Review in Journal of pharmaceutical investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 216 citations in OpenAlex.
- Alkylsuccinylated Bentonite-GelMA Hybrid Hydrogels for Enhanced Mechanics and Osteogenic Drug Delivery.ACS omega · 2026Article
- Bifidobacterium animalis subsp. lactis GOLDGUT-BB69 Counteracts Diarrhea in Mice by Alleviating Inflammation, Enhancing Intestinal Barrier Functions, and Regulating Intestinal Microbiota.Probiotics and antimicrobial proteins · 2026Article
- Effect of diosmectite on the pharmacokinetics of osimertinib in rats.Scientific reports · 2026Article
- Quercetin and Its Nano-Based Formulations Against Skin Cancer: A Narrative Review.Health science reports · 2026Article
- Cyclodextrin-Based Nanogels with Chemistry-Tunable Intracellular Stability and Distribution.International journal of nanomedicine · 2026Article
- MontmorilloniteEco-friendly and Effective Catalyst in the Synthesis of Biologically Active Compounds with Bicyclo[3.3.1] Moiety.ACS omega · 2025Article
- Multifunctional Liposomes: Smart Nanomaterials for Enhanced Photodynamic Therapy.Biomimetics (Basel, Switzerland) · 2025Review
- Nanostructured Clays Used as Carriers for Controlled Delivery of Antibacterial Compounds From Direct Restorative Dental Materials: A Scoping Review.Clinical and experimental dental research · 2025Article
- A Review on Novel Formulations and Delivery Systems of Botanical Insecticides for Enhanced Efficacy.Neotropical entomology · 2025Review
- Sustainable sodium alginate hydrogels incorporating banana leaf activated carbon and organo-clay for enhanced dye removal.Scientific reports · 2025Article
- Survival of Filamentous Cyanobacteria Through Martian ISRU: Combined Effects of Desiccation and UV-B Radiation.Microorganisms · 2025Article
- Article
- The potential cutaneous benefits of bentonites and montmorillonites.Archives of dermatological research · 2024Review
- The Use of Organoclays as Excipient for Metformin Delivery: Experimental and Computational Study.Molecules (Basel, Switzerland) · 2024Article
- Structure and Intercalation of Cysteine-Asparagine-Serine Peptide into Montmorillonite as an Anti-Inflammatory Agent Preparation-A DFT Study.Molecules (Basel, Switzerland) · 2024Article
- Preparation and evaluation of proliposomes formulation for enhancing the oral bioavailability of ginsenosides.Journal of ginseng research · 2024Article
- Review
- Bentonite in Korea: A Resource and Research Focus for Biomedical and Cosmetic Industries.Materials (Basel, Switzerland) · 2024Review
- Protective Effects of Carbonated Chitosan Montmorillonite on Vomitoxin-Induced Intestinal Inflammation.Polymers · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Montmorillonite is a multifunctional clay mineral and a major component of bentonite. Montmorillonite has been used in various industrial and pharmaceutical fields due to its unique characteristics, which include swelling and adsorption. The high adsorption capacity of montmorillonite contributes to increase drug entrapment and sustained-release of drugs. Montmorillonite generally sustains drug release in many formulations by strongly adsorbing to the drug. In addition, montmorillonite enhances the dissolution rate and bioavailability of hydrophobic drugs. Moreover, montmorillonite was applied to form composites with other polymer-based delivery systems. Thus, montmorillonite could be applied to formulate diverse drug delivery systems to control and/or improve the pharmaceutical properties of drugs, including solubility, dissolution rate, and absorption. In this review, perspectives of applying montmorillonite as a pharmaceutical excipient in drug delivery systems are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.