ReviewComputational and structural biotechnology journal2020
NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for
Review in Computational and structural biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 123 citations in OpenAlex.
- CeOPlant molecular biology · 2026Review
- Review on Predictive Models and Integration Strategies for Holistic Impact Assessment of Chemicals and Materials.Environmental science & technology · 2026Review
- Atom-level descriptors and explainable prediction of iron carbide nanoparticles' cytotoxicityNanoscale advances · 2026Article
- Safe and sustainable by design with ML/AI: A transformative approach to advancing nanotechnology.Beilstein journal of nanotechnology · 2026Article
- Recent Advances in Machine Learning Models for Predicting Toxicity of Inorganic Nanoparticles.Chem & bio engineering · 2025Review
- Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials.Environmental science & technology · 2025Article
- Characterising Dissolution Dynamics of Engineered Nanomaterials: Advances in Analytical Techniques and Safety-by-Design.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- CompSafeNano project: NanoInformatics approaches for safe-by-design nanomaterials.Computational and structural biotechnology journal · 2025Article
- Computational and structural biotechnology meets nanoscience and advanced materials.Computational and structural biotechnology journal · 2024Article
- ASCOT: A web tool for the digital construction of energy minimized Ag, CuO, TiOComputational and structural biotechnology journal · 2024Article
- Comprehensive insights into mechanism of nanotoxicity, assessment methods and regulatory challenges of nanomedicines.Discover nano · 2024Review
- Modeling onActa pharmaceutica Sinica. B · 2024Article
- Predicting blood-brain barrier permeability of molecules with a large language model and machine learning.Scientific reports · 2024Article
- Nanosimilars: A Scientific or A Regulatory Debate?The AAPS journal · 2024Review
- Biomolecular Adsorption on Nanomaterials: Combining Molecular Simulations with Machine Learning.Journal of chemical information and modeling · 2024Article
- Mining, refining, and QSAR analysing the nanoinformatics in EPA NaKnowBase.Environmental science. Nano · 2024Article
- Iron Overload in Brain: Transport Mismatches, Microbleeding Events, and How Nanochelating Therapies May Counteract Their Effects.International journal of molecular sciences · 2024Review
- Biomolecular Adsorprion at ZnS Nanomaterials: A Molecular Dynamics Simulation Study of the Adsorption Preferences, Effects of the Surface Curvature and Coating.Nanomaterials (Basel, Switzerland) · 2023Article
- Glyphosate Separating and Sensing for Precision Agriculture and Environmental Protection in the Era of Smart Materials.Environmental science & technology · 2023Review
- A curated gene and biological system annotation of adverse outcome pathways related to human health.Scientific data · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
53 authors at 20 institutions in 17 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanotechnology has enabled the discovery of a multitude of novel materials exhibiting unique physicochemical (PChem) properties compared to their bulk analogues. These properties have led to a rapidly increasing range of commercial applications; this, however, may come at a cost, if an association to long-term health and environmental risks is discovered or even just perceived. Many nanomaterials (NMs) have not yet had their potential adverse biological effects fully assessed, due to costs and time constraints associated with the experimental assessment, frequently involving animals. Here, the available NM libraries are analyzed for their suitability for integration with novel nanoinformatics approaches and for the development of NM specific Integrated Approaches to Testing and Assessment (IATA) for human and environmental risk assessment, all within the NanoSolveIT cloud-platform. These established and well-characterized NM libraries (e.g. NanoMILE, NanoSolutions, NANoREG, NanoFASE, caLIBRAte, NanoTEST and the Nanomaterial Registry (>2000 NMs)) contain physicochemical characterization data as well as data for several relevant biological endpoints, assessed in part using harmonized Organisation for Economic Co-operation and Development (OECD) methods and test guidelines. Integration of such extensive NM information sources with the latest nanoinformatics methods will allow NanoSolveIT to model the relationships between NM structure (morphology), properties and their adverse effects and to predict the effects of other NMs for which less data is available. The project specifically addresses the needs of regulatory agencies and industry to effectively and rapidly evaluate the exposure, NM hazard and risk from nanomaterials and nano-enabled products, enabling implementation of computational 'safe-by-design' approaches to facilitate NM commercialization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.