Evidence map›Paper›PMID 32226484›Full record

ArticleAnalytical methods : advancing methods and applications2020

Optical Nanosensors for

Wenjun Di, Heather A Clark

Open access · greenAbstract read
In one paragraph

Article in Analytical methods : advancing methods and applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Wenjun DiDepartment of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0002-1662-311X
Heather A ClarkDepartment of Bioengineering, Northeastern University, Boston, Massachusetts 02115, United States.ORCID 0000-0002-2628-9194
Northeastern University · US

Funding

Tufts Clinical and Translational Science Institute (Pilot Supplement)UL1TR002544 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2018 to 2022
$50.2M
Circulating Red Blood Cell Based Nanosensors for Continuous, Real-Time Drug MonitoringR01EB024186 · NIBIB · NORTHEASTERN UNIVERSITY · PI CLARK, HEATHER A, NIEDRE, MARK JONATHAN · 2018 to 2021
$1.6M
NCATS NIH HHS UL1 TR002544NIBIB NIH HHS R01 EB024186
6 · The paper itself

Abstract

Personalized approaches for continuous monitoring of chloride levels are potentially valuable for evaluating the efficacy of new treatments of genetic disorders such as cystic fibrosis. In this report, we validated optode-based nanosensors for real-time chloride monitoring in the interstitial fluid of living animals. These nanosensors take advantage of a ratiometric sensing scheme which demonstrates reversible and selective chloride detection in the physiological range. We further investigate how skin pigmentation affects the sensor performance during

Indexed as

ChloridesCystic FibrosisAnimalsDiagnostic ImagingFluorescenceMiceChlorides

Identifiers

PMID32226484
PMCPMC7100910
OpenAlexW3008771050

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.