Evidence map›Paper›PMID 32226427›Full record

ReviewFrontiers in immunology2020

Transcriptional Regulators of T Helper 17 Cell Differentiation in Health and Autoimmune Diseases.

Alessia Capone, Elisabetta Volpe

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 181 citations in OpenAlex.

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  14. CD4Frontiers in immunology · 2026
    Review
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  20. Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alessia CaponeNeuroimmunology Unit, IRCSS Fondazione Santa Lucia, Rome, Italy.
Elisabetta VolpeNeuroimmunology Unit, IRCSS Fondazione Santa Lucia, Rome, Italy.
Fondazione Santa Lucia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T helper (Th) 17 cells are a subtype of CD4 T lymphocytes characterized by the expression of retinoic acid-receptor (RAR)-related orphan receptor (ROR)γt transcription factor, encoded by gene

Indexed as

Gene Expression RegulationAutoimmune DiseasesBasic-Leucine Zipper Transcription FactorsCell DifferentiationHumansHypoxia-Inducible Factor 1, alpha SubunitInterleukin-17Nuclear Receptor Subfamily 1, Group F, Member 3STAT3 Transcription FactorTh17 CellsTranscription, GeneticBasic-Leucine Zipper Transcription FactorsBATF protein, humanHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitInterleukin-17Nuclear Receptor Subfamily 1, Group F, Member 3RORC protein, humanSTAT3 Transcription FactorCrohn's diseaseinterleukin-17multiple sclerosispsoriasisretinoic acid receptor related orphan nuclear receptor γtrheumatoid arthritisT helper 17 cells

Identifiers

PMID32226427
PMCPMC7080699
OpenAlexW3012147355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.