Evidence map›Paper›PMID 32226394›Full record

ArticleFrontiers in physiology2020

Angiotensin-(1-7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice.

Anne Järve, Fatimunnisa Qadri, Mihail Todiras, Shirley Schmolke, Natalia Alenina, Michael Bader

Abstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne JärveMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.
Fatimunnisa QadriMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.
Mihail TodirasMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.
Shirley SchmolkeMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.
Natalia AleninaMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.
Michael BaderMax Delbrück Center for Molecular Medicine, Helmholtz Association of German Research Centers, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental spinal cord injury (SCI) causes a morphological and functional deterioration of the heart, in which the renin-angiotensin system (RAS) might play a role. The recently discovered non-canonical axis of RAS with angiotensin-(1-7) and its receptor Mas, which is associated with cardioprotection could be essential to prevent damage to the heart following SCI. We investigated the cardiac consequences of SCI and the role of Mas in female wild-type (WT,

Indexed as

atrogenescardiac atrophyfibrosisrenin–angiotensin systemsympathetic nervous system

Identifiers

PMID32226394
PMCPMC7080696

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.