ArticleReumatologia2019
Effects of whole body cryotherapy in patients with rheumatoid arthritis considering immune parameters.
Article in Reumatologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- The untapped potential of cold water therapy as part of a lifestyle intervention for promoting healthy aging.GeroScience · 2025Review
- Effects of whole-body cryostimulation on spinal and shoulder range of motion in individuals with obesity.Frontiers in rehabilitation sciences · 2025Article
- Whole-Body Cryotherapy Reduces Systemic Inflammation in Healthy Adults: Pilot Cohort Study.Interactive journal of medical research · 2024Article
- Machine learning-based remission prediction in rheumatoid arthritis patients treated with biologic disease-modifying anti-rheumatic drugs: findings from the Kuwait rheumatic disease registry.Frontiers in big data · 2024Article
- Whole-Body Cryostimulation, a Complementary Treatment for Phantom Limb Syndrome: Preliminary Evidence from a Case Study.Medicina (Kaunas, Lithuania) · 2023Article
- Clinical Spectrum and Trajectory of Innovative Therapeutic Interventions for Insomnia: A Perspective.Aging and disease · 2023Article
- Effects of Whole-Body Cryostimulation on Pain Management and Disease Activity in Active Rheumatic Polymyalgia: A Case-Report.Biomedicines · 2023Article
- Innate immunity changes in soccer players after whole-body cryotherapy.BMC sports science, medicine & rehabilitation · 2022Article
- Use of Cryotherapy for Managing Chronic Pain: An Evidence-Based Narrative.Pain and therapy · 2021Review
- Improving the quality of life of patients with rheumatoid arthritis after rehabilitation irrespective of the level of disease activity.Rheumatology international · 2021Article
- Effects of whole-body cryotherapy on the innate and adaptive immune response in cyclists and runners.Immunologic research · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWhole body cryotherapy (WBC) is widely used in inflammatory diseases of the joints, including rheumatoid arthritis (RA), but the mechanism(s) of its action is not fully understood. The aim of the study was to compare the effects of WBC and conventional rehabilitation (CR) on the clinical and immune status of RA patients. MATERIAL AND
methodsRheumatoid arthritis patients were classified into 2 groups according to the rehabilitation method used: the study group (CT,
resultsAfter rehabilitation disease activity (DAS28), morning stiffness and pain intensity (VAS) decreased in both patient groups and no statistically significant differences were observed between them. However, statistically significant improvement in the CRP serum level was observed in the CT group only. No differences were observed in the serum concentrations of tested cytokines either before and after rehabilitation, or between patient groups.
conclusionsWe report that regardless of the type of therapy, comprehensive rehabilitation improves the patient's clinical status, but has no effect on the levels of circulating cytokines, such as IL-6, IL-10, TNF-α, and MIF, despite significant reduction of a systemic inflammatory marker (CRP), especially in the CT group.
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