ArticlePloS one2020
Secondary spontaneous pneumothorax and bullous lung disease in cannabis and tobacco smokers: A case-control study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Vaping-Associated Pneumothorax: A Systematic Review of Case Reports and Case Series.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Predictors and Prevention of Recurrence After Secondary Spontaneous Pneumothorax: A Systematic Review.Cureus · 2026Review
- Spontaneous Pneumothorax: A Review of Underlying Etiologies and Diagnostic Imaging Modalities.Tomography (Ann Arbor, Mich.) · 2025Review
- Tension Pneumothorax Requiring Video-Assisted Thoracoscopic Surgery With Multimodal Pleurodesis: An Unexpected Ramification of a Ground Level Fall Without Significant Blunt or Penetrating Injury.Respirology case reports · 2025Article
- CT features associated with contralateral recurrence of spontaneous pneumothorax.QJM : monthly journal of the Association of Physicians · 2024Article
- Article
- Spontaneous Pneumothorax Secondary to Bullous Lung Emphysema Positive for Cannabinoids upon Toxicological Examination.Journal of clinical medicine · 2023Article
- Clearing up the smoke: Physical and mental health considerations regarding cannabis use in adolescents with cystic fibrosis.Pediatric pulmonology · 2023Review
- Article
- Recurrent Spontaneous Pneumothorax Associated With Marijuana Abuse: Case Report and Literature Review.Cureus · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe notion that smoking cannabis may damage the respiratory tract has been introduced in recent years but there is still a paucity of studies on this subject. The aim of this study was to investigate the relationship between cannabis smoking, pneumothorax and bullous lung disease in a population of operated patients. METHODS AND
findingsWe performed a retrospective study on patients operated on for spontaneous pneumothorax. Patients were divided into three groups according to their smoking habit: cannabis smokers, only-tobacco smokers and nonsmokers. Cannabis lifetime exposure was expressed in dose-years (1d/y = 1 gram of cannabis/week for one year). Clinical, radiological and perioperative variables were collected. The variables were analyzed to find associations with smoking habit. The impact of the amount of cannabis consumption was also investigated by ROC curves analysis. Of 112 patients, 39 smoked cannabis, 23 smoked only tobacco and 50 were nonsmokers. Median cannabis consumption was 28 dose/years, median tobacco consumption was 6 pack/years. Cannabis smokers presented with more severe chronic respiratory symptoms and bullous lung disease and with a higher incidence of tension pneumothorax than both tobacco smokers and nonsmokers. Cannabis smokers also developed a larger pneumothorax, experienced prolonged postoperative stay and demonstrated a higher incidence of pneumothorax recurrence after the operation than nonsmokers did. The risk of occurrence of chronic respiratory symptoms and bullous lung disease in cannabis smokers was dose-related.
conclusionsCannabis smoking seems to increase the risk of suffering from respiratory complaints and can have detrimental effects on lung parenchyma, in a dose-dependent manner. Cannabis smoking also negatively affected the outcome of patients operated for spontaneous pneumothorax. A history of cannabis abuse should always be taken in patients with pneumothorax. There may be need for a specific treatment for pneumothorax in cannabis smokers.
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