Evidence map›Paper›PMID 32225103›Full record

ReviewMolecules (Basel, Switzerland)2020

An Appraisal of Antidotes' Effectiveness: Evidence of the Use of Phyto-Antidotes and Biotechnological Advancements.

Christiana Eleojo Aruwa, Yusuf Ola Mukaila, Abdulwakeel Ayokun-Nun Ajao, Saheed Sabiu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Delayed treatment with hydro-ethanolic extract ofPharmaceutical science advances · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Christiana Eleojo AruwaDepartment of Biotechnology and Food Technology, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa.ORCID 0000-0003-4979-8968
Yusuf Ola MukailaDepartment of Botany, Obafemi Awolowo University, Ile-Ife 220005, Nigeria.
Abdulwakeel Ayokun-Nun AjaoDepartment of Botany and Plant Biotechnology, University of Johannesburg, P.O. Box 524, Auckland Park APK 2006, South Africa.ORCID 0000-0003-3820-2559
Saheed SabiuDepartment of Biotechnology and Food Technology, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa.ORCID 0000-0001-7209-9220
Durban University of Technology · ZAObafemi Awolowo University · NGUniversity of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poisoning is the greatest source of avoidable death in the world and can result from industrial exhausts, incessant bush burning, drug overdose, accidental toxication or snake envenomation. Since the advent of Albert Calmette's cobra venom antidote, efforts have been geared towards antidotes development for various poisons to date. While there are resources and facilities to tackle poisoning in urban areas, rural areas and developing countries are challenged with poisoning management due to either the absence of or inadequate facilities and this has paved the way for phyto-antidotes, some of which have been scientifically validated. This review presents the scope of antidotes' effectiveness in different experimental models and biotechnological advancements in antidote research for future applications. While pockets of evidence of the effectiveness of antidotes exist

Indexed as

AnimalsAntidotesBiotechnologyDisease Models, AnimalDrug DevelopmentDrug Evaluation, PreclinicalHumansPhytochemicalsPoisoningTreatment OutcomeAntidotesPhytochemicalsantidotesphyto-antidotespoisonssecondary metabolitessnakebitessnake envenomation

Identifiers

PMID32225103
PMCPMC7181008
OpenAlexW3013256528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.