Evidence map›Paper›PMID 32224841›Full record

ArticleGenomics & informatics2020

Bioinformatics services for analyzing massive genomic datasets.

Gunhwan Ko, Pan-Gyu Kim, Youngbum Cho, Seongmun Jeong, Jae-Yoon Kim, Kyoung Hyoun Kim, Ho-Yeon Lee, Jiyeon Han, Namhee Yu, Seokjin Ham and 12 more

Abstract read
In one paragraph

Article in Genomics & informatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Gunhwan KoKorea Bioinformation Center (KOBIC), KRIBB, Daejeon 34141, Korea.
Pan-Gyu KimKorea Bioinformation Center (KOBIC), KRIBB, Daejeon 34141, Korea.
Youngbum ChoGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Seongmun JeongGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Jae-Yoon KimGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Kyoung Hyoun KimGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Ho-Yeon LeeGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Jiyeon HanDepartment of BioInformation Science, Ewha Womans University, Seoul 03760, Korea.
Namhee YuDepartment of BioInformation Science, Ewha Womans University, Seoul 03760, Korea.
Seokjin HamDepartment of Life Sciences and Division of Integrative Biosciences & Biotechnology, Pohang University of Science & Technology (POSTECH), Pohang 37673, Korea.
Insoon JangDepartment of Life Sciences and Division of Integrative Biosciences & Biotechnology, Pohang University of Science & Technology (POSTECH), Pohang 37673, Korea.
Byunghee KangDepartment of Life Sciences and Division of Integrative Biosciences & Biotechnology, Pohang University of Science & Technology (POSTECH), Pohang 37673, Korea.
Sunguk ShinDepartment of Systems, Biology Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Lian KimBioposh Inc., Daejeon 34016, Korea.
Seung-Won LeeSeqGenesis, Daejeon 34016, Korea.
Dougu NamSchool of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Korea.
Jihyun F KimDepartment of Systems, Biology Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Namshin KimGenome Editing Research Center, KRIBB, Daejeon 34141, Korea.
Seon-Young KimGenome Structure Research Center, KRIBB, Daejeon 34141, Korea.
Sanghyuk LeeDepartment of BioInformation Science, Ewha Womans University, Seoul 03760, Korea.
Tae-Young RohDepartment of Life Sciences and Division of Integrative Biosciences & Biotechnology, Pohang University of Science & Technology (POSTECH), Pohang 37673, Korea.
Byungwook LeeKorea Bioinformation Center (KOBIC), KRIBB, Daejeon 34141, Korea.

Funding

National Research Foundation of Korea 2014M3C9A3064548National Research Foundation of Korea 2014M3C9A3064552National Research Foundation of Korea 2014M3C9A3065221National Research Foundation of Korea 2014M3C9A3068554National Research Foundation of Korea 2014M3C9A3068822National Research Foundation of Korea 2019M3C9A5069653
6 · The paper itself

Abstract

The explosive growth of next-generation sequencing data has resulted in ultra-large-scale datasets and ensuing computational problems. In Korea, the amount of genomic data has been increasing rapidly in the recent years. Leveraging these big data requires researchers to use large-scale computational resources and analysis pipelines. A promising solution for addressing this computational challenge is cloud computing, where CPUs, memory, storage, and programs are accessible in the form of virtual machines. Here, we present a cloud computing-based system, Bio-Express, that provides user-friendly, cost-effective analysis of massive genomic datasets. Bio-Express is loaded with predefined multi-omics data analysis pipelines, which are divided into genome, transcriptome, epigenome, and metagenome pipelines. Users can employ predefined pipelines or create a new pipeline for analyzing their own omics data. We also developed several web-based services for facilitating downstream analysis of genome data. Bio-Express web service is freely available at https://www.bioexpress.re.kr/.

Indexed as

analysis pipelinecloud computinggenomic dataweb serverworkflow system

Identifiers

PMID32224841
PMCPMC7120352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.