ArticleAging2020
Clinical significance of age at diagnosis among patients with thymic epithelial tumors: a population-based study.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Survival and relapse of Danish patients with thymic epithelial tumors.Acta oncologica (Stockholm, Sweden) · 2026Article
- Clinical Evaluation of T Component in the Ninth Edition TNM Classification of Thymic Epithelial Tumors.Thoracic cancer · 2025Article
- Long-Term Outcomes of Thymoma Treated at a Single Institute.South Asian journal of cancer · 2025Article
- Differentiating thymic epithelial tumors from mediastinal lymphomas: preoperative nomograms based on PET/CT radiomic features to minimize unnecessary anterior mediastinal surgery.Journal of cancer research and clinical oncology · 2023Article
- Prognostic value of preoperative chemotherapy for thymic epithelial tumors: A propensity-matched analysis based on the SEER database.Frontiers in surgery · 2023Article
- Pathological tumor long-to-short axis ratio as a prognostic factor in patients with thymic epithelial tumors.Thoracic cancer · 2022Article
- A novel risk classifier for predicting the overall survival of patients with thymic epithelial tumors based on the eighth edition of the TNM staging system: A population-based study.Frontiers in endocrinology · 2022Article
- The Studies of Prognostic Factors and the Genetic Polymorphism of Methylenetetrahydrofolate Reductase C667T in Thymic Epithelial Tumors.Frontiers in oncology · 2022Article
- Development of a competing risk nomogram for the prediction of cause-specific mortality in patients with thymoma: a population-based analysis.Journal of thoracic disease · 2021Article
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Authors and funding
5 authors.
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Abstract
backgroundTo investigate the clinicopathologic characteristics and survival outcomes of patients with thymic epithelial tumors (TET) according to age at diagnosis.
resultsA total of 4431 patients were analyzed. Gender, race, tumor histology and surgery were similar between different age groups. The 0-18 group was associated with a higher risk of distant metastasis. Compared to patients aged above 80, the hazard ratios (HR) for patients aged 0-18, 19-30, 31-40, 41-50, 51-60, 61-70, 71-80 were 1.079, 0.739, 0.614, 0.621, 0.633, 0.673, 0.861, respectively. From the subgroup analysis for the adult patients who were above 19 years old, we found that the 19-70 group had significant better cancer specific survival (CSS) and overall survival (OS) than the above 70 group.
conclusionsAge is a strong independent prognostic factor for survival in TET. Pediatric TET has a higher risk of distant metastasis and an inferior CSS. For the adults who were above 19, patients older than 70-year-old were associated with a shorter CSS.
methodsInformation of 4431 TET patients was retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. Demographic features, clinicopathologic characteristics and survival outcomes were compared between patients diagnosed at different age groups (0-18, 19-30, 31-40, 41-50, 51-60, 61-70, 71-80, above 80).
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