Evidence map›Paper›PMID 32224036›Full record

ArticleAcademic radiology2021

Portable Perfusion Phantom Offers Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Accurate Prostate Cancer Grade Stratification: A Pilot Study.

Harrison Kim, John V Thomas, Jeffrey W Nix, Jennifer B Gordetsky, Yufeng Li, Soroush Rais-Bahrami

Open access · hybridAbstract read
In one paragraph

Article in Academic radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Quantitative Prostate MRI, From theAJR. American journal of roentgenology · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Harrison KimDepartment of Radiology, University of Alabama at Birmingham, G082C5 Volker Hall, 1670 University Blvd., Birmingham, AL 35294-0019; O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, Birmingham, AL. Electronic address: hyunkikim@uabmc.edu.
John V ThomasDepartment of Radiology, University of Alabama at Birmingham, G082C5 Volker Hall, 1670 University Blvd., Birmingham, AL 35294-0019.
Jeffrey W NixDepartment of Urology, University of Alabama at Birmingham, Birmingham, Alabama; O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, Birmingham, AL.
Jennifer B GordetskyDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama.
Yufeng LiDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Soroush Rais-BahramiDepartment of Radiology, University of Alabama at Birmingham, G082C5 Volker Hall, 1670 University Blvd., Birmingham, AL 35294-0019; Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama; O'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, Birmingham, AL.
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
NCI NIH HHS P30 CA013148
6 · The paper itself

Abstract

RATIONALE AND

objectivesThe study goal was to test whether the improved accuracy in quantitative dynamic contrast-enhanced magnetic resonance imaging measurement using a point-of-care portable perfusion phantom (P4) leads to better stratification of prostate cancer grade. MATERIALS AND

methodsA prospective clinical study was conducted recruiting 44 patients scheduled for multi-parameter MRI prostate exams. All participants were imaged with the P4 placed under their pelvic regions. Tissue sampling was carried out for 25 patients at 22 ± 18 (mean ± SD) days after multi-parameter MRI. On histologic examination, a total of 31 lesions were confirmed as prostate cancer. Tumors were classified into low grade (n = 14), intermediate grade (n = 10), and high grade (n = 7). Tumor perfusion was assessed by volume transfer constant, K

resultsAfter P4-based error correction, the K

conclusionThe P4 allows to reduce errors in quantitative dynamic contrast-enhanced magnetic resonance imaging measurement, enhancing accuracy in stratification of prostate cancer grade.

Indexed as

Contrast MediaProstatic NeoplasmsHumansMagnetic Resonance ImagingMalePerfusionPilot ProjectsProspective StudiesContrast MediaDCE-MRIGrade stratificationPerfusion phantomProstate cancer

Identifiers

PMID32224036
PMCPMC7529802
OpenAlexW3013664666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.