Evidence map›Paper›PMID 32223900›Full record

ArticleeLife2020

Simranjot Bawa, David S Brooks, Kathryn E Neville, Marla Tipping, Md Abdul Sagar, Joseph A Kollhoff, Geetanjali Chawla, Brian V Geisbrecht, Jason M Tennessen, Kevin W Eliceiri and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  10. Review
  11. Hypoxia-inducible factor-driven glycolytic adaptations in host-microbe interactions.Pflugers Archiv : European journal of physiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Simranjot BawaDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, United States.ORCID 0000-0003-3837-3868
David S BrooksDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, United States.
Kathryn E NevilleDepartment of Biology, Providence College, Providence, United States.
Marla TippingDepartment of Biology, Providence College, Providence, United States.
Md Abdul SagarLaboratory for Optical and Computational Instrumentation, Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0002-1564-0727
Joseph A KollhoffDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, United States.
Geetanjali ChawlaRegional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad-Gurgaon Expressway, Faridabad, India.
Brian V GeisbrechtDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, United States.
Jason M TennessenDepartment of Biology, Indiana University, Bloomington, United States.ORCID 0000-0002-3527-5683
Kevin W EliceiriLaboratory for Optical and Computational Instrumentation, Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0001-8678-670X
Erika R GeisbrechtDepartment of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, United States.ORCID 0000-0002-1450-7166
Kansas State University · USProvidence College · USUniversity of Wisconsin–Madison · USIndiana University Bloomington · USRegional Centre for Biotechnology · IN

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
A Drosophila Model for the Regulation of Aerobic GlycolysisR35GM119557 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Jason Michael Tennessen · 2016 to 2026
$4.7M
Mechanisms Underlying Muscle Development in DrosophilaR01AR060788 · NIAMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI Erika Rae Geisbrecht · 2012 to 2026
$4.3M
Metabolic defects promote pathogenesis in a Drosophila model of muscular dystrophyR21AR073373 · NIAMS · KANSAS STATE UNIVERSITY · PI GEISBRECHT, ERIKA RAE · 2018 to 2019
$364k
Mechanisms Underlying Muscle Development and Maintenance in DrosophilaR56AR060788 · NIAMS · KANSAS STATE UNIVERSITY · PI GEISBRECHT, ERIKA RAE · 2018 to 2018
$339k
NIAMS NIH HHS R01 AR060788NIAMS NIH HHS R21 AR073373NIAMS NIH HHS R56 AR060788NIGMS NIH HHS P20 GM103430NIGMS NIH HHS R35 GM119557
6 · The paper itself

Abstract

Cell growth and/or proliferation may require the reprogramming of metabolic pathways, whereby a switch from oxidative to glycolytic metabolism diverts glycolytic intermediates towards anabolic pathways. Herein, we identify a novel role for TRIM32 in the maintenance of glycolytic flux mediated by biochemical interactions with the glycolytic enzymes Aldolase and Phosphoglycerate mutase. Loss of

Indexed as

Cell ProliferationAnimalsCell CycleDrosophila melanogasterDrosophila ProteinsGlucoseGlycolysisLarvaTripartite Motif ProteinsUbiquitin-Protein LigasesDrosophila ProteinsGlucosetn protein, DrosophilaTripartite Motif ProteinsUbiquitin-Protein Ligasescancercancer biologycell biologyD. melanogasterDrosophilaglycolysismetabolismmuscleTRIM32

Identifiers

PMID32223900
PMCPMC7105379
OpenAlexW3014079563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.