Evidence map›Paper›PMID 32223755›Full record

ArticleCell communication and signaling : CCS2020

Unusually persistent Gα

Isabelle Ziffert, Anette Kaiser, Stefanie Babilon, Karin Mörl, Annette G Beck-Sickinger

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Cell communication and signaling : CCS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Neuropeptide Y Peptide Family and Cancer: Antitumor Therapeutic Strategies.International journal of molecular sciences · 2023
    Review
  5. DynamicNano letters · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. NPY and Gene Therapy for Epilepsy: How, When,... and Y.Frontiers in molecular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Isabelle ZiffertInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, D-04103, Leipzig, Germany.
Anette KaiserInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, D-04103, Leipzig, Germany.
Stefanie BabilonInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, D-04103, Leipzig, Germany.
Karin MörlInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, D-04103, Leipzig, Germany.
Annette G Beck-SickingerInstitute of Biochemistry, Faculty of Life Sciences, Leipzig University, Brüderstr. 34, D-04103, Leipzig, Germany. abeck-sickinger@uni-leipzig.de.
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA sensitive balance between receptor activation and desensitization is crucial for cellular homeostasis. Like many other GPCR, the human neuropeptide Y MATERIALS: We studied the desensitization and activatability of recycled Y

resultsWe observed strong desensitization of the Y

conclusionThe unusually persistent Gα

Indexed as

GTP-Binding Protein alpha Subunits, Gi-GoHEK293 CellsHumansNeuropeptide YProtein BindingReceptors, Neuropeptide YSignal TransductionGTP-Binding Protein alpha Subunits, Gi-GoNeuropeptide Yneuropeptide Y2 receptorReceptors, Neuropeptide YDesensitizationGPCRG proteinInternalizationNeuropeptide YNeuropeptide Y receptors

Identifiers

PMID32223755
PMCPMC7104545
OpenAlexW3013130019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.