Evidence map›Paper›PMID 32223553›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2020

Quantitative proteomic and phosphoproteomic profiling of ischemic myocardial stunning in swine.

Xue Wang, Xiaomeng Shen, Brian R Weil, Rebeccah F Young, John M Canty, Jun Qu

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Proteomics of the heart.Physiological reviews · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Myocardial stunning and hibernation revisited.Nature reviews. Cardiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xue WangDepartment of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York.
Xiaomeng ShenNew York State Center of Excellence in Bioinformatics and Life Sciences, University at Buffalo, Buffalo, New York.
Brian R WeilDepartment of Physiology and Biophysics, University at Buffalo, Buffalo, New York.ORCID 0000-0002-8832-6771
Rebeccah F YoungClinical and Translational Research Center, University at Buffalo, Buffalo, New York.
John M CantyDepartment of Physiology and Biophysics, University at Buffalo, Buffalo, New York.
Jun QuDepartment of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York.
University at Buffalo, State University of New York · USRoswell Park Comprehensive Cancer Center · USVA Western New York Healthcare System · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Metabolic Adaptation and Functional Recovery of Hibernating MyocardiumR01HL061610 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 2000 to 2018
$6.0M
CHRONIC ADAPTATIONS TO MYOCARDIAL ISCHEMIAR01HL055324 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 1996 to 2014
$4.2M
Amplification of Cardiosphere-Derived Cell TherapyF32HL114335 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WEIL, BRIAN RAYMOND · 2013 to 2015
$159k
Preventing and Reversing Interstitial Fibrosis in HFpEFI01BX002659 · VA · VA WESTERN NEW YORK HEALTHCARE SYSTEM · PI Brian Raymond Weil · 2016 to 2026
–
BLRD VA I01 BX002659NCATS NIH HHS UL1 TR001412NHLBI NIH HHS F32 HL114335NHLBI NIH HHS R01 HL055324NHLBI NIH HHS R01 HL061610
6 · The paper itself

Abstract

Despite decades of research on the pathophysiology of myocardial stunning, protein changes and/or phosphorylation status underlying alterations in cardiac function/structure remain inadequately understood. Here, we utilized comprehensive and quantitative proteomic and phosphoproteomic approaches to explore molecular mechanisms of myocardial stunning in swine. The closed-chest swine (

Indexed as

Action PotentialsAnimalsCoronary DiseaseMaleMyocardial ContractionMyocardiumPhosphoproteinsProtein KinasesProteomeSwinePhosphoproteinsProtein KinasesProteomeapoptosiscontractile dysfunctionextracellular matrixmyocardial stunningquantitative proteomics and phosphoproteomicsRNA-seq-derived databaseswine heart protein database

Identifiers

PMID32223553
PMCPMC7346541
OpenAlexW3013339746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.