Evidence map›Paper›PMID 32223396›Full record

ArticleJournal of the American Heart Association2020

Sex-Related Differences in Patients at High Bleeding Risk Undergoing Percutaneous Coronary Intervention: A Patient-Level Pooled Analysis From 4 Postapproval Studies.

Rishi Chandiramani, Davide Cao, Bimmer E Claessen, Sabato Sorrentino, Paul Guedeney, Moritz Blum, Ridhima Goel, Anastasios Roumeliotis, Mitchell Krucoff, Ken Kozuma and 13 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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  4. Sex differences in coronary artery disease.Naunyn-Schmiedeberg's archives of pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 7 countries.

Rishi ChandiramaniThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Davide CaoThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Bimmer E ClaessenThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Sabato SorrentinoThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Paul GuedeneyThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Moritz BlumThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Ridhima GoelThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Anastasios RoumeliotisThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Mitchell KrucoffDuke University Medical Center Durham NC.
Ken KozumaTeikyo University Tokyo Japan.
Junbo GeZhongshan Hospital Fudan University Shanghai China.
Ashok SethFortis Escorts Heart Institute New Delhi India.
Raj MakkarCedars-Sinai Medical Center Los Angeles CA.
Sripal BangaloreNew York University Langone Medical Center New York NY.
Deepak L BhattBrigham and Women's Hospital Heart and Vascular Center Harvard Medical School Boston MA.
Dominick J AngiolilloDivision of Cardiology University of Florida College of Medicine-Jacksonville Jacksonville FL.
Karine RusterAbbott Vascular Santa Clara CA.
Jin WangAbbott Vascular Santa Clara CA.
Shigeru SaitoShonan Kamakura General Hospital Kamakura Japan.
Franz-Josef NeumannUniversity of Freiburg Germany.
James HermillerSt Vincent's Medical Center of Indiana Indianapolis IN.
Marco ValgimigliBern University Hospital Bern Switzerland.
Roxana MehranThe Zena and Michael A. Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai New York NY.
Cardiovascular Institute of the South · USAbbott (United States) · USBrigham and Women's Hospital · USCedars-Sinai Medical Center · USDuke Medical Center · USFortis Escorts Heart Institute · INInserm · FRNYU Langone Health · USShonan Kamakura General Hospital · JPSt. Vincent's Medical Center · USSun Yat-sen University · CNTeikyo University Hospital · JPUniversity Hospital of Bern · CHUniversity of Florida · USUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Women have been associated with higher rates of recurrent events after percutaneous coronary intervention than men, possibly attributable to advanced age at presentation and greater comorbidities. These factors also put women at higher risk of bleeding, which may influence therapeutic strategies and clinical outcomes. Methods and Results We performed a patient-level pooled analysis of 4 postapproval registries to evaluate sex-related differences in patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention. HBR required fulfillment of at least 1 major or 2 minor criteria of the Academic Research Consortium definition. Outcomes of interest were major bleeding and major adverse cardiac events (composite of cardiac death, myocardial infarction, or definite/probable stent thrombosis). Of the total 10 502 patients, 2832 (27.0%) were women. The prevalence of HBR was higher in women compared with men (29.0% versus 20.5%,

Indexed as

AgedAged, 80 and overCoronary Artery DiseaseDrug-Eluting StentsDual Anti-Platelet TherapyFemaleHemorrhageHumansMaleMiddle AgedPercutaneous Coronary InterventionPrevalenceRecurrenceRegistriesRetrospective StudiesRisk Assessmenteverolimus‐eluting stenthigh bleeding riskmajor bleedingpercutaneous coronary interventionsex

Identifiers

PMID32223396
PMCPMC7428610
OpenAlexW3013043430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.