Evidence map›Paper›PMID 32223394›Full record

ArticleJournal of the American Heart Association2020

Decoupling Between Diastolic Pulmonary Artery and Pulmonary Capillary Wedge Pressures Is Associated With Right Ventricular Dysfunction and Hemocompatibility-Related Adverse Events in Patients With Left Ventricular Assist Devices.

Teruhiko Imamura, Nikhil Narang, Gene Kim, Jayant Raikhelkar, Ben Chung, Ann Nguyen, Luise Holzhauser, Daniel Rodgers, Sara Kalantari, Bryan Smith and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Teruhiko ImamuraDepartment of Medicine University of Chicago Medical Center Chicago IL.
Nikhil NarangAdvocate Heart Institute Advocate Christ Medical Center Oak Lawn IL.
Gene KimDepartment of Medicine University of Chicago Medical Center Chicago IL.
Jayant RaikhelkarDivision of Cardiology Columbia University Medical Center New York NY.
Ben ChungDepartment of Medicine University of Chicago Medical Center Chicago IL.
Ann NguyenDepartment of Medicine University of Chicago Medical Center Chicago IL.
Luise HolzhauserDepartment of Medicine University of Chicago Medical Center Chicago IL.
Daniel RodgersDepartment of Medicine University of Chicago Medical Center Chicago IL.
Sara KalantariDepartment of Medicine University of Chicago Medical Center Chicago IL.
Bryan SmithDepartment of Medicine University of Chicago Medical Center Chicago IL.
Takeyoshi OtaDepartment of Surgery University of Chicago Medical Center Chicago IL.
Tae SongDepartment of Surgery University of Chicago Medical Center Chicago IL.
Colleen JuricekDepartment of Surgery University of Chicago Medical Center Chicago IL.
Daniel BurkhoffDivision of Cardiology Columbia University Medical Center New York NY.
Valluvan JeevanandamDepartment of Surgery University of Chicago Medical Center Chicago IL.
Gabriel SayerDivision of Cardiology Columbia University Medical Center New York NY.
Nir UrielDivision of Cardiology Columbia University Medical Center New York NY.
University of Chicago Medical Center · USColumbia University Irving Medical Center · USAdvocate Christ Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Decoupling between diastolic pulmonary artery pressure and pulmonary capillary wedge pressure is an index of pulmonary vascular damage. This study assessed the impact of decoupling on right heart function and hemocompatibility-related adverse events. Methods and Results In this prospective study, patients underwent invasive hemodynamic tests following left ventricular assist device implantation. Decoupling was defined as a difference of >5 mm Hg between diastolic pulmonary artery pressure and pulmonary capillary wedge pressure. Among 92 patients with left ventricular assist devices (median age, 61 years; 57% male), 44 patients (48%) had decoupling. Right heart function and size by echocardiographic assessment worsened during a 1-year observational period in the decoupling group as compared with the control group (

Indexed as

Arterial PressureHeart-Assist DevicesPulmonary Wedge PressureAgedFemaleGastrointestinal HemorrhageHeart FailureHumansHypertension, PulmonaryMaleMiddle AgedProspective StudiesProsthesis ImplantationPulmonary ArteryRisk FactorsThrombosisbleedinghemodynamicspulmonary hypertensionunloading

Identifiers

PMID32223394
PMCPMC7428624
OpenAlexW3013380453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.