Evidence map›Paper›PMID 32223225›Full record

ArticleChemical research in toxicology2020

Yael-Natalie H Escobar, Grace Nipp, Tianqu Cui, Sarah S Petters, Jason D Surratt, Ilona Jaspers

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. The respiratory epithelium in the era of vaping: insights fromEuropean respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  8. Article
  9. NAM journal · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yael-Natalie H Escobar
Grace NippDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, North Carolina 27599, United States.
Tianqu CuiDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, North Carolina 27599, United States.
Sarah S PettersDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, North Carolina 27599, United States.
Jason D SurrattDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-6833-1450
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
The Impact of Tobacco Exposure on the Lungs Innate Defense SystemP50HL120100 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RANDELL, SCOTT H · 2013 to 2017
$21.0M
TOXICOLOGYT32ES007126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ILONA JASPERS, Bernard E. Weissman · 1985 to 2026
$13.0M
E-cig flavors and their effects on respiratory innate immune responsesR01HL139369 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA · 2017 to 2020
$2.4M
FDA HHSNHLBI NIH HHS P50 HL120100NHLBI NIH HHS R01 HL139369NIEHS NIH HHS P30 ES010126NIEHS NIH HHS T32 ES007126
6 · The paper itself

Abstract

In the United States, the recent surge of electronic cigarette (e-cig) use has raised questions concerning the safety of these devices. This study seeks to assess the pro-inflammatory and cellular stress effects of the vaped humectants propylene glycol (PG) and glycerol (GLY) on airway epithelial cells (16HBE cells and differentiated human bronchial epithelial cells) with a newly developed aerosol exposure system. This system allows for chemical characterization of e-cig generated aerosol particles as well as

Indexed as

Electronic Nicotine Delivery SystemsAerosolsBronchiCells, CulturedCytokinesEpithelial CellsGlycerolHumansHygroscopic AgentsOxidative StressParticle SizePropylene GlycolVapingAerosolsCytokinesGlycerolHygroscopic AgentsPropylene Glycol

Identifiers

PMID32223225
PMCPMC11391858
OpenAlexW3013147125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.