Evidence map›Paper›PMID 32223222›Full record

ArticleACS nano2020

Osteotropic Radiolabeled Nanophotosensitizer for Imaging and Treating Multiple Myeloma.

Rui Tang, Alexander Zheleznyak, Matthew Mixdorf, Anchal Ghai, Julie Prior, Kvar C L Black, Monica Shokeen, Nathan Reed, Pratim Biswas, Samuel Achilefu

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Nanomedicine-Based Strategies for Multiple Myeloma Therapy.International journal of nanomedicine · 2026
    Review
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  4. Article
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  7. Recent advances in targeted drug delivery systems for multiple myeloma.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rui TangDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.ORCID 0000-0002-2734-1003
Alexander ZheleznyakDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Matthew MixdorfDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Anchal GhaiDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Julie PriorDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Kvar C L BlackDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Monica ShokeenDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Nathan ReedDepartment of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri 63112, United States.
Pratim BiswasDepartment of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri 63112, United States.ORCID 0000-0003-1104-3738
Samuel AchilefuDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.ORCID 0000-0002-3133-6717
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
WU-MDACC Inter-Institutional Molecular Imaging CenterP50CA094056 · NCI · WASHINGTON UNIVERSITY · PI PIWNICA-WORMS, DAVID · 2002 to 2016
$26.3M
Project 2 - Radiation-Induced Treatment of Multiple Myeloma using NanoparticlesU54CA199092 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2019
$11.5M
DEVELOPMENT OF GOGGLE SYSTEM FOR FLUORESCENCE IMAGE-GUIDED SURGERYR01CA171651 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2013 to 2017
$2.8M
NANOPHOTOSENSITIZERS FOR REGENERATIVE PHOTOTHERAPY OF TUMORSR01EB021048 · NIBIB · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2020
$2.3M
IVIS Spectrum CT Preclinical In Vivo Imaging SystemS10OD027042 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2019 to 2019
$599k
Multispectral Optoacoustic Tomography (MSOT) SystemS10OD025264 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2018 to 2018
$544k
FLUORESCENCE MOLECULAR TOMOGRAPHY SYSTEMS10OD020129 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2015
$330k
FLUORESCENCE LIFETIME IMAGING MICROSCOPY SYSTEMS10OD016237 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2014 to 2014
$267k
NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA094056NCI NIH HHS R01 CA171651NCI NIH HHS U54 CA199092NIBIB NIH HHS R01 EB021048NIH HHS S10 OD016237NIH HHS S10 OD020129NIH HHS S10 OD025264NIH HHS S10 OD027042
6 · The paper itself

Abstract

Rapid liver and spleen opsonization of systemically administered nanoparticles (NPs) for

Indexed as

Multiple MyelomaAnimalsMicePositron-Emission TomographyPositron Emission Tomography Computed TomographyRadioisotopesTissue DistributionZirconiumRadioisotopesZirconiumcancerCerenkov radiationmultiple myelomananoparticlesZr-89

Identifiers

PMID32223222
PMCPMC7295119
OpenAlexW3013198364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.