Evidence map›Paper›PMID 32222992›Full record

ArticleJournal of medical virology2020

Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia.

Tongqiang Zhang, Xiaojian Cui, Xue Zhao, Jinhu Wang, Jiafeng Zheng, Guifen Zheng, Wei Guo, Chunquan Cai, Sijia He, Yongsheng Xu

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 18 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 18 syntheses or guidelines pooled it, 239 citations in OpenAlex.

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  2. When to test for COVID-19 using real-time reverse transcriptase polymerase chain reaction: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
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  7. Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis.European journal of obstetrics, gynecology, and reproductive biology · 2021
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tongqiang ZhangDepartment of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.ORCID 0000-0002-6945-1868
Xiaojian CuiDepartment of Clinical Laboratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Xue ZhaoDepartment of Clinical Laboratory, Shenyang Coloproctology Hospital, Liaoning, China.
Jinhu WangDepartment of Neonatal Surgery, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Jiafeng ZhengDepartment of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Guifen ZhengDepartment of Imaging, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Wei GuoDepartment of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Chunquan CaiDepartment of Neurosurgery, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Sijia HeNational Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia.ORCID 0000-0002-1932-1141
Yongsheng XuDepartment of Respiratory, The Children's Hospital of Tianjin (Children's Hospital of Tianjin University), Tianjin, China.
Tianjin University · CNGeorge Mason University · USShenyang Anorectal Hospital · CN

Funding

Program of Tianjin Science and Technology Plan 18ZXDBSY00170
6 · The paper itself

Abstract

Coronavirus Disease 2019 (COVID-19) is a newly emerging infectious disease caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). After its first occurrence in Wuhan of China from December 2019, COVID-19 rapidly spread around the world. According to the World Health Organization statement on 13 March 2020, there had been over 132 500 confirmed cases globally. Nevertheless, the case reports of children are rare, which results in the lack of evidence for preventing and controlling of children's infection. Here, we report three cases of SARS-CoV-2 infected children diagnosed from 3 February to 17 February 2020 in Tianjin, China. All of these three cases experienced mild illness and recovered soon after the treatment, with the nucleic acid of throat swab turning negative within 14, 11, and 7 days after diagnosis, respectively. However, after been discharged, all three cases were tested SARS-CoV-2 positive in the stool samples within 10 days, in spite of their remained negative nucleic acid in throat swab specimens. Therefore, it is necessary to be aware of the possibility of fecal-oral transmission of SARS-CoV-2 infection, especially for children cases.

Indexed as

ConvalescenceAscorbic AcidBetacoronavirusBiomarkersCeftriaxoneChildChinaClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingDrugs, Chinese HerbalFecesHumansInterferonsMaleAscorbic AcidBiomarkersCeftriaxoneDrugs, Chinese HerbalInterferonsRibavirinRNA, Viralchildrenclinical characteristicsCOVID-19SARS-CoV-2

Identifiers

PMID32222992
PMCPMC7228213
OpenAlexW3014088366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.