Evidence map›Paper›PMID 32222944›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2020

Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity.

Mathew Vadukoot Lazar, Malini Eapen, Harikumar R Nair, Ismail Siyad, Rajesh Gopalakrishna

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Comparison of clinical and metabolic profiles of lean versus non-lean nonalcoholic fatty liver disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mathew Vadukoot LazarDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O., Kochi, 682 041, India.
Malini EapenDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O., Kochi, 682 041, India.
Harikumar R NairDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O., Kochi, 682 041, India.
Ismail SiyadDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O., Kochi, 682 041, India.
Rajesh GopalakrishnaDepartment of Gastroenterology, Amrita Institute of Medical Sciences, Kochi, Amrita Vishwa Vidyapeetham, AIMS Ponekkara P.O., Kochi, 682 041, India. grajesh22@gmail.com.ORCID 0000-0003-1101-5737
Amrita Institute of Medical Sciences and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInsulin resistance (IR) plays a central role in pathogenesis of nonalcoholic steatohepatitis (NASH). The aim of this study was to correlate histopathological grading and IR in overweight/obese patients with NASH as compared with lean NASH.

methodsPatients with NASH who underwent liver biopsy between January 2012 and December 2012 were included. Anthropometric, clinical, and biochemical features, necro-inflammatory grades, and fibrosis stage on liver biopsies were scored according to Brunt and non-alcoholic fatty liver disease (NAFLD) activity score (NAS).

resultsOf 42 patients, 33 (78.6%) had body mass index (BMI) ≥ 23 kg/m

conclusionsAlthough IR was significantly higher in overweight/obese patients with NASH as compared with that in lean patients with NASH, there was no difference in the correlation of HOMA-IR with histology between these groups.

Indexed as

Insulin ResistanceFemaleHumansLiverMaleNon-alcoholic Fatty Liver DiseaseBrunt scoreCirrhosisFatty liverObesity

Identifiers

PMID32222944
OpenAlexW3014040916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.