Evidence map›Paper›PMID 32222846›Full record

ArticleCellular and molecular neurobiology2021

Bradykinin Receptors Play a Critical Role in the Chronic Post-ischaemia Pain Model.

Elaine C D Gonçalves, Graziela Vieira, Tainara R Gonçalves, Róli R Simões, Indiara Brusco, Sara M Oliveira, João B Calixto, Maíra Cola, Adair R S Santos, Rafael C Dutra

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Analgesic and Psychotropic Effects of a New Bradykinin Antagonist.Bulletin of experimental biology and medicine · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Kinin BScientific reports · 2023
    Article
  12. Kinin BPharmaceutics · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Elaine C D GonçalvesLaboratory of Autoimmunity and Immunopharmacology, Department of Health Sciences, Campus Araranguá, Federal University of Santa Catarina, Araranguá, SC, 88906-072, Brazil.ORCID http://orcid.org/0000-0003-0682-3019
Graziela VieiraLaboratory of Autoimmunity and Immunopharmacology, Department of Health Sciences, Campus Araranguá, Federal University of Santa Catarina, Araranguá, SC, 88906-072, Brazil.
Tainara R GonçalvesLaboratory of Autoimmunity and Immunopharmacology, Department of Health Sciences, Campus Araranguá, Federal University of Santa Catarina, Araranguá, SC, 88906-072, Brazil.
Róli R SimõesLaboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.ORCID http://orcid.org/0000-0002-0906-6001
Indiara BruscoGraduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.ORCID http://orcid.org/0000-0003-1816-2924
Sara M OliveiraGraduate Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, 97105-900, Brazil.
João B CalixtoCenter of Innovation and Preclinical Research, Florianópolis, SC, 88056-000, Brazil.ORCID http://orcid.org/0000-0003-4041-7153
Maíra ColaLaboratory of Autoimmunity and Immunopharmacology, Department of Health Sciences, Campus Araranguá, Federal University of Santa Catarina, Araranguá, SC, 88906-072, Brazil.
Adair R S SantosLaboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, 88040-900, Brazil.ORCID http://orcid.org/0000-0002-6435-4698
Rafael C DutraLaboratory of Autoimmunity and Immunopharmacology, Department of Health Sciences, Campus Araranguá, Federal University of Santa Catarina, Araranguá, SC, 88906-072, Brazil. rafaelcdutra@gmail.com.ORCID http://orcid.org/0000-0002-6938-2161
Universidade Federal de Santa Catarina · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex regional pain syndrome type-I (CRPS-I) is a chronic painful condition resulting from trauma. Bradykinin (BK) is an important inflammatory mediator required in acute and chronic pain response. The objective of this study was to evaluate the association between BK receptors (B

Indexed as

AnimalsBradykinin Receptor AntagonistsCholinesterase InhibitorsChronic PainDisease Models, AnimalFemaleGene Expression RegulationGene SilencingHyperalgesiaIschemiaMaleMiceNociceptionReceptors, BradykininSpinal CordBradykinin Receptor AntagonistsCholinesterase InhibitorsReceptors, BradykininBradykinin receptor antagonistsChronic painHyperalgesiaInflammationInflammatory mediatorsKinins

Identifiers

PMID32222846
PMCPMC11448614
OpenAlexW3013430356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.