ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
ETV in infancy and childhood below 2 years of age for treatment of hydrocephalus.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 24 citations in OpenAlex.
- Modern Aspects of Post-haemorrhagic Hydrocephalus in Infants: Current Challenges and Prospects.Korean journal of neurotrauma · 2025Review
- Research status of fetal hydrocephalus from 2003 to 2022 based on bibliometric analysis.Ibrain · 2025Review
- Pediatric shunt failure in a resource limited Lower-Middle Income Country (LMIC) institution in La Paz, Bolivia.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- "Various factors affecting the success of the ETV procedure in infants"-an insight via a prospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- The endoscopic treatment of fourth ventricle outlet obstruction: Report of two children and systematic review.Clinical case reports · 2023Article
- Optimal therapeutic strategies for pineal region lesions.Frontiers in neurology · 2023Article
- Long-term neurological cognitive, behavioral, functional, and quality of life outcomes after fetal myelomeningocele closure: a systematic review.Clinical and experimental pediatrics · 2023Article
- Endoscopic third ventriculostomy: a feasible treatment option for pediatric hydrocephalus in a high-risk cohort - a single-center report.World journal of pediatric surgery · 2022Article
- Tumor-related hydrocephalus in infants: a narrative review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Early Detection of Hydrocephalus in Infant Presenting Aqueductal Stenosis after Endoscopic Third Ventriculostomy: Two Case Reports.Journal of medical ultrasoundArticle
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Authors and funding
13 authors at 5 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
purposeAge and etiology play a crucial role in success of endoscopic third ventriculostomy (ETV) as a treatment of obstructive hydrocephalus. Outcome is worse in infants, and controversies still exist whether ETV is superior to shunt placement. We retrospectively analyzed 70 patients below 2 years from 4 different centers treated with ETV and assessed success.
methodsChildren < 2 years who received an ETV within 1994-2018 were included. Patients were classified according to age and etiology; < 3, 4-12, and 13-24 months, etiologically; aqueductal stenosis, post-hemorrhagic-hydrocephalus (PHH), tumor-related, fourth ventricle outflow obstruction, with Chiari-type II and following CSF infection. We investigated statistically the predictors for ETV success through computing Kaplan-Meier estimates using patient's follow-up time and time to ETV failure.
resultsWe collected 70 patients. ETV success rate was 41.4%. The highest rate was in tumor-related hydrocephalus and fourth ventricle outlet obstruction (62.5%, 60%) and the lowest rate was in Chiari-type II and following infection (16.7%, 0%). The below 3 months age group showed relatively lower success rate (33.3%) in comparison to older groups which showed similar results (46.4%, 46.6%). Statistically, a previous VP shunt was a predictor for failure (p value < 0.05).
conclusionFactors suggesting a high possibility of failure were age < 3 months and etiology such as Chiari-type II or following infection. Altered CSF dynamics in patients with PHH and under-developed arachnoid villi may play a role in ETV failure. We do not recommend ETV as first line in children < 3 months of age or in case of Chiari II or following infection.
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