Evidence map›Paper›PMID 32222480›Full record

Observational studyJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2020

Transesophageal Echocardiography, Mortality, and Length of Hospitalization after Cardiac Valve Surgery.

Emily J MacKay, Mark D Neuman, Lee A Fleisher, Prakash A Patel, Jacob T Gutsche, John G Augoustides, Nimesh D Desai, Peter W Groeneveld

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Emily J MacKayDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania; Penn's Cardiovascular Outcomes, Quality and Evaluative Research Center, Philadelphia, Pennsylvania; Penn Center for Perioperative Outcomes Research and Transformation, Philadelphia, Pennsylvania; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: emily.mackay@pennmedicine.upenn.edu.
Mark D NeumanDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania; Penn Center for Perioperative Outcomes Research and Transformation, Philadelphia, Pennsylvania; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania.
Lee A FleisherDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania.
Prakash A PatelDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania; Penn Center for Perioperative Outcomes Research and Transformation, Philadelphia, Pennsylvania.
Jacob T GutscheDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania.
John G AugoustidesDepartment of Anesthesiology & Critical Care, Philadelphia, Pennsylvania.
Nimesh D DesaiDivision of Cardiovascular Surgery, Philadelphia, Pennsylvania; Penn's Cardiovascular Outcomes, Quality and Evaluative Research Center, Philadelphia, Pennsylvania; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania.
Peter W GroeneveldDepartment of Internal Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Penn's Cardiovascular Outcomes, Quality and Evaluative Research Center, Philadelphia, Pennsylvania; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania.
Penn Center for AIDS Research · US

Funding

Training in Critical Care Health Policy ResearchT32HL098054 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Scott D Halpern · 2010 to 2026
$8.2M
NHLBI NIH HHS T32 HL098054
6 · The paper itself

Abstract

backgroundDespite recommendations regarding the use of intraoperative transesophageal echocardiography (TEE), there is no randomized evidence to support its use in cardiac valve surgery. The purpose of this study was to compare the clinical outcomes of patients undergoing open cardiac valve repair or replacement surgery with and without transesophageal echocardiographic monitoring. The hypothesis was that transesophageal echocardiographic monitoring would be associated with lower 30-day mortality and shorter length of hospitalization.

methodsIn this observational retrospective cohort study, Medicare claims were used to test the association between perioperative TEE and 30-day all-cause mortality and length of hospitalization among patients undergoing open cardiac valve repair or replacement surgery between January 1, 2010, and October 1, 2015. Baseline characteristics were defined by inpatient and outpatient claims. Medicare death records were used to ascertain 30-day mortality. Statistical analyses included regression models and propensity score matching.

resultsA total of 219,238 patients underwent open cardiac valve surgery, of whom 85% underwent TEE. Patients who underwent TEE were significantly older and had greater comorbidities. After adjusting for patient demographics, clinical comorbidities, surgical characteristics, and hospital factors, including annual surgical volume, the TEE group had a lower adjusted odds of 30-day mortality (odds ratio, 0.77; 95% CI, 0.73 to 0.82; P < .001), with no difference in length of hospitalization (<0.01%; 95% CI, -0.61% to 0.62%; P = .99). Results were similar across all analyses, including a propensity score-matched cohort.

conclusionsTransesophageal echocardiographic monitoring in cardiac valve repair or replacement surgery was associated with lower 30-day risk-adjusted mortality, without a significant increase in length of hospitalization. These findings support the use of TEE as routine practice in open cardiac valve repair or replacement surgery.

Indexed as

Echocardiography, TransesophagealMedicareAgedHeart ValvesHospitalizationHumansRetrospective StudiesUnited StatesCardiovascular surgeryComparative effectiveness researchHealth services researchOutcomes researchTransesophageal echocardiography

Identifiers

PMID32222480
PMCPMC7276287
OpenAlexW3013612570

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.